Lediga jobb som Biokemist i Mölndal

Do you have a passion for chemical compliance, sustainability, and making a real impact in the Life Science industry? Are you motivated by turning complex regulations into meaningful solutions? Then this might be the role for you!
As a Chemical Compliance and Sustainability Specialist (kemikalie- och hållbarhetsspecialist), you will be part of our Regulatory Affairs department consisting of two colleagues, responsible for ensuring global compliance with regulations and legislation for IVD products. You will take the lead on chemical and environmental compliance, while also be part of a collaborative team where we share experiences, support one another, and maintain a positive, open atmosphere. This role offers the best of both worlds: the independence to shape your own responsibilities, and the strong backing of dedicated colleagues who value teamwork and knowledge sharing. It is a unique opportunity to make an impact in both compliance and sustainability while developing in a future-focused environment. 
Examples of tasks:
ensure that the company complies with relevant chemical and environmental regulations. 
responsible for conducting chemical risk assessments and classifying solutions in compliance with applicable regulations.
administer and further develop the company’s chemical management system and ensure the accuracy of chemical inventories and classifications. 
provide training and internal guidance on safe chemical handling and risk communication. 
conduct and support environmental reporting, including CSRD/ESRS compliance. 
be responsible for audits and inspections related to environmental and chemical compliance. 
collaborate across departments (e.g., Quality, R&D, Production) to align chemical safety and sustainability practices.

Qualifications
We believe you are a self-driven and collaborative person with a genuine interest in sustainability and safe chemical management. To succeed in the role, you combine initiative and responsibility with openness and teamwork, contributing to a positive atmosphere and meaningful progress in our sustainability efforts.
Requirements:
have a university degree in chemistry, environmental science, biotechnology, or similar. 
practical experience from working in a laboratory. 
strong ability to structure, document, and report technical data. 
excellent skills in Swedish and English, both spoken and written.

Meritorious skills and experience:
knowledge of chemical legislation, e.g. REACH/CLP.
knowledge of national legislation, e.g. the Swedish Environmental code (Miljöbalken), Swedish Work Environment Authority (Arbetsmiljöverkets föreskrifter) and flammable products (Myndigheten för samhällsskydd och beredskaps författningssamlingar).
experience with quality management systems (e.g. ISO 13485).
experience working with chemical safety systems and regulatory tools. 
familiarity with sustainability reporting standards (e.g., CSRD/ESRS). 
experience in internal training, audit preparation, or environmental risk analysis.

Interested? 
This is a full-time, permanent position. Start date by agreement.
If you have any questions regarding the position you are welcome to contact the hiring manager Linnéa, [email protected]
To apply, please register your profile and send in your application as soon as possible but no later than September 15, 2025. Visa mindre

Job description
Thesis Project: Bioorthogonal Labeling of Proteins for Biochemical Assays
If you’re inspired by the possibilities of science to make a difference and ready to discover what you can do – join us!

Thesis type: 60 credit
Project start: January 2023
Student location: On Site, Gothenburg Sweden

Background: Biochemical assays are critical in several stages of drug discovery, including high-throughput screening (HTS), lead optimization, and studies of structure-activity-relationship (SAR) and mode-of-action (MoA). A large proportion of drug targets are proteins for which the only known biological function is ligand binding. Such targets require biochemical assays that can measure the interaction between the protein target and a ligand. Often the protein target is expressed as a fusion protein with an affinity tag that can be indirectly “labelled” by a fluorophore-conjugated antibody or other labelled affinity reagent. While this strategy is often successful, it is resource intensive to produce the many protein variants that may need to be tested and there is a significant cost for the labelled affinity reagents. An alternative approach is to directly conjugate a fluorophore to the protein target of interest using a bioorthogonal chemical reaction resulting in a protein target covalently bound to a fluorophore while maintaining its biological activity. Examples of such reactions are amine- or thiol-coupling using N-hydroxysuccinimide- or maleimide-activated fluorophores, respectively. This research is aimed at exploring bioorthogonal protein labelling for biochemical assays and establish a generic labelling protocol for biochemical time-resolved FRET assays.
Hypothesis: Covalently attaching fluorophores to protein targets will result in robust biochemical FRET assays and reduce resource requirements for assay development.
Purpose: Generate fluorophore-conjugated proteins for use in fluorescence applications such as biochemical binding assays to simplify and streamline assay development.

At AstraZeneca, all of our employees make a difference to patients’ lives every day. We operate in more than 100 countries around the world and are one of Sweden’s most important export companies.
 
With more than 2,400 employees from 50 countries, the vibrant Gothenburg site helps to support the entire life-cycle of AstraZeneca medicines, from drug discovery and clinical trials, to global commercialisation and product maintenance. Gothenburg is one of AstraZeneca’s three strategic, global R&D centres, alongside Cambridge and Gaithersburg, and plays a central role in our mission to deliver life-changing medicines to patients.



Responsibilities
Investigate bioorthogonal labelling for a number of protein targets
Optimize labelling reaction conditions and sample purification procedures
Determine the site of labeling by mass spectrometry
Optimize the methodology to achieve site-specific 1:1 labelling
Establish a generic protocol to reproducibly generate fluorophore-conjugated proteins using bioorhtogonal chemical reactions
Develop FRET assays using fluorophore-conjugated proteins and compare to FRET assays that use other affinity reagents such as antibodies






Qualifications
Essential to role:
Strong background in biochemistry
Practical biochemical laboratory experience, including pipetting, handling of solid and liquid chemicals, handling of biomolecules
Good understanding of protein chemistry, including protein purification
Good understanding of biochemical assays and ligand binding kinetics
Good understanding of fluorescence and FRET


Additional desired skills:
Practical experience in biochemical assays and/or protein purification
Practical experience of pipetting small volumes of liquid (<10 µl)
Good understanding of organic chemistry
Good understanding of statistics




Application
2022-10-18, welcome with your application at www.randstad.se.


For more information: contact Malin Fridholm, [email protected]

About the company
If you’re inspired by the possibilities of science to make a difference and ready to discover what you can do – join us! 

At AstraZeneca we are guided in our work by a strong set of values, and we’re resetting expectations of what a bio-pharmaceutical company can be. By truly following the science, we pioneer new methods, new thinking and bring unexpected teams together. From scientists to sales, lab techs to legal, we’re on a mission to turn ideas into life-changing medicines that transform lives. We need great people who share our passion for science and have the drive and determination to meet the unmet needs of patients around the world. If you’re swift to action, confident to lead, willing to collaborate, and curious about what science can do, then you’re our kind of person.

AstraZeneca is an equal opportunity employer. AstraZeneca will consider all qualified applicants for employment without discrimination on grounds of disability, sex or sexual orientation, pregnancy or maternity leave status, race or national or ethnic origin, age, religion or belief, gender identity or re-assignment, marital or civil partnership status, protected veteran status (if applicable) or any other characteristic protected by law. AstraZeneca only employs individuals with the right to work in the country/ies where the role is advertised. Visa mindre

Utbildning:
?Mastersexamen inom kemi / kemiteknik / bioteknik eller liknande, gärna med erfarenhet från att arbeta med biomaterial eller annan medicinteknik
Krav:
· God labbvana
· Erfarenhet från att arbeta med ytanalystekniker som SEM, EDX och XPS
· Goda kunskaper i engelska, såväl i tal som i skrift
Meriterande:
· Kemist inom biomaterial med 3-5 års arbetslivserfarenhet
· Kunskap inom kvalitetsarbete (ISO 13485)
· Tidigare arbete inom biomaterial eller annan medicinteknik
· Körkort
Ansvarsområden:
Att planera och driva utvecklingsprojekt tillsammans med övriga medlemmar i vår teknikgrupp och den beställande kunden. En stor del av tjänsten innebär att arbeta på labb med utveckling av Promimics tekniker för att modifiera dentala och ortopediska implantat, och analysarbete med hjälp av SEM / EDX och andra metoder för ytanalys. I arbetsuppgifterna ingår även skriftlig och muntlig rapportering av projekt till kund via digitala mötesverktyg eller vid fysiska möten.
Tjänsten:
Tjänsten är en heltidstjänst med start så snart som möjligt.
Om Promimic:
Promimic är ett tillväxtbolag som utvecklar och marknadsför biomaterial för förbättrad osseointegration till ledande företag inom dentala och ortopediska implantat. Huvudprodukten HAnano Surface har utvecklats från spetsforskning vid Chalmers tekniska högskola i Sverige. Tekniken har visat sig förbättra osseointegrationen i över 30 vetenskapliga studier och med över 700 000 implantat i klinisk användning. Promimic har kontor i Mölndal, Sverige och Austin, Texas, USA.
Kontakt: Har du frågor om tjänsten får du gärna kontakta Per Kjellin, CTO och grundare av Promimic via mail: [email protected] Visa mindre

Job description
Senior scientist protein production and protein biochemistry

Are you truly passionate about the magic that happens in the lab? Could you see yourself applying your protein science knowledge in a successful pharmaceutical company? Would you like to join a team of highly skilled scientists where both your professional and personal skills are valued?
We have an exciting opportunity for you to join us working within a dynamic scientific environment to support drug discovery. The Discovery Biology department within Discovery Sciences is responsible for the generation of novel reagents and assays to support projects in all phases of the drug discovery pipeline. We focus on scientific advances in small molecules, oligonucleotides and other new technologies and drug discovery platforms across our different core areas.

Our stunning campus in Gothenburg is one of AstraZeneca’s three strategic science centres. The site is home to several thousand employees, from 50 different nationalities. Gothenburg includes the complete range of functions, and as such offers plenty of development opportunities for a wide variety of professionals. Our science teams in Gothenburg collaborate with academic and industry partners in Sweden and globally. And the site itself is designed with collaboration in mind. From the Coffee Lab to exercise areas, we’ve built a series of environments where innovation can happen.

Responsibilities
Essential Requirements:
MSc degree with significant experience from pharmaceutical or biotechnology industry or PhD in Biology, Pharmacology, Biochemistry or other a related discipline
Expertise in Protein Science through a demonstrable knowledge of construct design, molecular biology, protein expression, purification, characterization and structure function
Proven knowledge of a wide range of methods and technologies applied to the expression, purification as well as characterization of recombinant proteins. E.g. bacterial expression, liquid chromatography, SDS-PAGE, mass spectrometry and biophysical techniques
Excellent analytical skills, good scientific judgement and communication skills
Excellent team working and networking skills with experience of interacting effectively in multi-disciplinary and cultural settings

Desirable Requirements:
Experience of producing and characterising nucleic acid binding proteins


Qualifications
Main Duties and Responsibilities
You will be responsible for producing and characterizing recombinant precise genome editing enzymes and to characterize for different applications to enable drug discovery. These proteins are used to enable new exciting modalities such as cell therapy and precise genome editing. Since this position is lab based, we expect that you have a true real passion for practical duties.

We will rely on you to:
Deliver expertise in recombinant protein expression purification and characterization
Work in partnership with colleagues in a cross functional setting to ensure the delivery of high-quality protein reagents to projects
Contribute with novel ideas and using discernment and knowledge where appropriate to influence the work of the project
Maintain an awareness of current developments in the literature and contribute to the continuous improvement process
Achieve personal as well as company scientific visibility through project contributions, presentations, publications and poster & oral conference presentations


Application
Deadline: 2022-03-04 , selection and interviews will be ongoing. The position may be filled before the last day of application, therefore, apply as soon as possible.

For more information:
Please contact Veronika Knudsen [email protected] or Jimmy Wadie [email protected] 

About the company
 Randstad Life Sciences is specialized in competences within Life Science. As a consultant with us, you get a competitive salary, benefits and collective agreements. Your consultant manager is always there for you and ensures that you get varying and developing assignments at different companies, within different industries. At Randstad Life Sciences, your personal development is in focus, and you are offered a large network and many activities.

Randstad Life Sciences specializes in the field of science and is part of Randstad, the world leader in recruitment and consulting with operations in 38 countries. With this global network, in combination with our strong local foundation, we can offer a wide range of varied and developing assignments and jobs for you who are a specialist in life science. Our mission is to help you reach your true potential with your career in focus! Visa mindre

Job description
At AstraZeneca, innovation is more than just research. As one of the world's leading pharmaceutical companies, we’re focused on providing medicines that make a real difference in patient care. AstraZeneca R&D Gothenburg is a great place to work where you can help us continue to lead the industry in research and development. It has an entrepreneurial and collaborative culture, where you’ll feel valued, energised and rewarded for your ideas and contributions. It is a place where talented people can immerse themselves in their work and make significant contributions towards scientific excellence.


You will join the Discovery Sciences organization, working within a vibrant scientific environment to support drug discovery. The Discovery Biology department of Discovery Sciences is responsible for the generation of novel reagents and assays to support projects in the IMED (Innovative Medicines and Early development) in all phases of the drug discovery pipeline, from target discovery all the way to clinical candidate. The IMED focuses on scientific advances in small molecules, oligonucleotides and other emerging technologies and drug discovery platforms across our different core areas.


There is an exciting opportunity for a talented and motivated individual to join the group in a lab-based role. The successful individual will be a key member of the team, contributing to and leading protein generation activities for a diverse range of projects across several disease areas and AstraZeneca sites globally. This is a temporary position, lasting for 6 months. 

Responsibilities
As a Research Scientist in the Biochemical Reagents team in Discovery Biology you will be responsible for producing and characterising recombinant proteins which represent disease targets for all small molecule drug discovery projects in the IMED, with a focus on Cardiovascular and Metabolic Disease (CVMD) and Respiratory, Inflammation and Autoimmunity (RIA) projects. Proteins are utilised for the development of biochemical assays for compound screening, structural/biophysical assays to characterise protein ligand interactions and to develop oligonucleotide drugs.

Main Duties and Responsibilities
To be a lab-based protein scientist, delivering recombinant proteins to support our projects
To provide expertise in the area of recombinant protein expression purification and characterisation.
To work in partnership with colleagues in Discovery Sciences and across therapy areas and sites to ensure the delivery of high-quality protein reagents to projects.
To deliver according to plans over agreed timelines such that the objectives of the project are met, including delivery of more than one agreed area of work in parallel where appropriate. 
To be an effective member of Drug Discovery Project Teams, contributing novel ideas and using judgment and knowledge where appropriate to influence the work of the project. 
To maintain an awareness of current developments in the literature and contribute to the continuous improvement process by identifying opportunities in the workplace where improvements can be made. 


Qualifications
Essential Requirements
BSc/MSc degree in biochemistry with significant relevant experience, preferably in the pharmaceutical or biotechnology industry. 
Expertise in the area of Protein Science through a demonstrable knowledge of construct design, molecular biology, protein expression, purification, characterisation and structure function.
 A practical understanding of a wide range of methods and technologies as applied to the expression, purification and characterisation of recombinant proteins. For example, bacterial expression, liquid chromatography.
Good problem-solving skills, good scientific judgement and communication skills.
Excellent team working and networking skills with experience of interacting effectively across teams



Desirable Requirements
PhD in biochemistry
Experience of parallel purification
Experience of purification of proteins from native sources.

For us, it is important that all competence and skills in the labor market are utilized. We welcome all applicants and strive for diversity.

Application
2020-02-02, selection and interviews will be ongoing. The position may be filled before the last day of application, therefore, apply as soon as possible.


For more information: Kerstin Karlsson [email protected] or Eleonor Ehrman +46733434109. 

About the company
Randstad Life Sciences is specialized in competences within Life Science. As a consultant with us, you get a competitive salary, benefits and collective agreements. Your consultant manager is always there for you and ensures that you get varying and developing assignments at different companies, within different industries. At Randstad Life Sciences, your personal development is in focus, and you are offered a large network and many social activities.


Randstad Life Sciences is part of Randstad, the world leader in recruitment and consulting with operations in 38 countries. With this global network, in combination with our strong local foundation, we can offer a wide range of varied and developing assignments and jobs for you who are a specialist in life science. Our mission is to help you reach your true potential with your career in focus! Visa mindre