Lediga jobb som Civilingenjör, bioteknik i Mölndal

Job description
Senior Research Scientist/Research Scientist – Genome Engineering
Imagine a future where a diagnosis of a severe genetic disease is no longer terrifying because effective medicines can cure them. At AstraZeneca, we are turning this vision into reality through pioneering work in genome editing and precision medicine. Join us in this effort!
Our Genome Engineering Team in Gothenburg, Sweden focuses on developing treatment for Rare Diseases. We continually push the boundaries of science to expand the limits of scientific research to better understand rare diseases, discover new life-changing treatments and deliver medicines to patients.
As a Senior Research Scientist, you will be a key member of the Genome Engineering Department. You will join our international team that develops novel genome engineering technologies and applies these breakthroughs to generate innovative gene therapies. We provide a stimulating environment with state-of-the-art facilities where you can transform cutting-edge genome engineering tools into effective and safe medicines.
What will you do:
In this laboratory-based role, you will leverage your scientific expertise in genome engineering and innovative thinking to develop novel tools and applications that can lead to breakthrough therapies. As a key member of cross-functional project teams, you will develop and evaluate genome editing strategies for specific disease projects.
Accountabilities will include innovative optimization of genome engineering technologies to facilitate effective gene editing in target cell & tissue types, developing relevant assays, analysing gene editing outcomes, documenting, interpreting, and communicating results to appropriate partners.
This is a consultant assignment with Randstad Life Sciences. Randstad Life Sciences is specialized in competences within Life Science. As a consultant you get a competitive salary, benefits and collective agreements. Your consultant manager ensures that you get varying and developing assignments at different companies, within different industries. At Randstad Life Sciences, your personal development is in focus, and you are offered a large network and many social activities.
Deadline 2026-02-13 - the selection process and interviews will be ongoing, so please apply as soon as possible!

Responsibilities
Your accountabilities will include:
Designing and evaluating therapeutic genome editing strategies for specific disease indications
Optimization of genome engineering technologies to facilitate effective gene editing in target cell & tissue types
Developing and routinely running appropriate assays for evaluating gene editing outcomes
Documenting, interpreting and communicating results to stakeholders and partners



Why AstraZeneca?
If you are passionate about translating scientific advances into real next generation medicines, AstraZeneca is the right place for you. Join the team to unlock the power of what science can do. You have the potential to grow yourself, our pipeline, and positively impact on the lives of billions of patients around the world.
What’s next? If this sounds like a good opportunity to you – welcome to apply today

Qualifications
Essential for the role:
PhD degree in life sciences or relevant areas with strong wet-lab skills, or MSc degree with equivalent experience
Strong skills in working with mammalian cell models (immortalized or primary)
Understanding and previous hands-on experience with CRISPR-Cas9 technologies
Strong skillset in standard molecular biology techniques in analyzing DNA, RNA and protein (e.g. PCR, sequencing technologies, RNA extraction, qPCR, Western blot, ELISA)
Strong communication skills, scientific rigor and ethics, ability to effectively work independently and collaboratively in a team

Desirable for the role:
Experience working with lentiviral vector for engineering cell models
Experience with using liquid handling instruments
Experience with optimizing genome editing technologies (construct design, gRNA optimization, delivery) or equivalent protein engineering expertise


About the company

Randstad
At Randstad, we see the possible in people. With business all over Sweden and in all areas of expertise, we help people find work that feels good, where they get the opportunity to develop and realize their true potential.
With close to 600 000 employees in 38 countries, Randstad is the global leader in the HR services industry. Our mission is to become the world’s most valued working life partner. By combining our passion for people with the power of today’s technology, we support people and organizations in realizing their true potential. We call it Human Forward. Visa mindre

Vi söker en engagerad medarbetare med några års labberfarenhet till vår utvecklingsavdelning i Mölndal för en tidsbegränsad anställning. Du blir en välkommen förstärkning till vårt team som idag består av ett 20-tal personer. Avdelningens huvudsakliga arbetsuppgift är utveckla immunoassays för diagnostik av neurodegenerativa sjukdomar och cancer samt att etablera nya monoklonala antikroppar som används som nyckelkomponenter i dessa tester.
Tjänsten
I rollen som Research and Development Scientist dina huvudsakliga arbetsuppgifter blir att deltaga i utveckling och prestandautvärdering av immunoassays på ett automatiserat IVD system. Du kan också komma att arbeta i projekt med utveckling, processoptimering och karaktärisering av immunoreagens för automatiserat IVD system.
Din bakgrund och kvalifikationer Högskoleutbildning inom biokemi, bioteknik, molekylärbiologi eller motsvarande.
Flera års erfarenhet av laboratoriearbete inom industriell eller akademisk miljö.
Erfarenhet av datahantering och statistiska beräkningar med användning av verktyg såsom Excel.
Utmärkta kommunikationsfärdigheter i svenska och engelska, i både i tal och skrift.
Meriterande erfarenheter Kunskap inom utveckling av immunoassays.
Erfarenhet av automatiserade system för immunoassays.
Erfarenhet av tillverkning av bioreagens, medicintekniska produkter eller läkemedel.
Arbetat enligt kvalitetsledningssystem, gärna ISO13485.
Vem är du?
Vi söker dig som med stort engagemang, eget driv och noggrannhet tar dig an ditt arbete. Vi värdesätter starkt samarbetsförmåga då effektivt samarbete är avgörande för att vi ska uppnå våra mål.
För att trivas och lyckas i rollen är det viktigt att du har en positiv inställning till din omgivning. Är du dessutom kvalitetsmedveten och strukturerad med förmåga att hålla tider i en verksamhet med många deadlines, så är det din profil vi söker.
Arbetsplats och kultur
Hos oss på Fujirebio hittar du en härlig gemenskap där vi jobbar tillsammans i en engagerande och dynamisk miljö för att leverera produkter som svarar mot kundernas förväntan, myndigheternas krav samt inte minst patienternas behov.
Anställning
Anställningen är en tidsbegränsad anställning under 14 månader med en omfattning på 100 % dagtid. Tillträde: 1 maj eller enligt överenskommelse.
Vill du veta mer?
Har du frågor om tjänsten, är du välkommen att kontakta rekryterande chef Eva Röijer, [email protected]
Välkommen med din ansökan
Skicka in din ansökan så snart som möjligt, dock senast 2 mars. Vi behandlar ansökningar löpande och tjänsten kan komma att tillsättas innan sista ansökningsdag. Observera att vi endast granskar CV:n utifrån vår kravprofil, så du behöver inte skicka med ett personligt brev. Vi ser fram emot din ansökan! Visa mindre

Job description
Senior Scientist in Process Analytical Technology (PAT) - Make a Meaningful Impact on People's Lives!
Are you ready to take your career to the next level and make a meaningful impact on people's lives with life-changing medicines? Join our Operations team in Gothenburg as a Senior Scientist and be part of a team where everyone feels a personal connection to the people we impact.
At AstraZeneca, our Operations team has a big ambition: to deliver more medicines to patients, quicker and more affordably. We are driven by our commitment to deliver accelerated growth for AstraZeneca and to make people's lives better.
In Pharmaceutical Technology and Development (PT&D), within Operations, we are the bridge between brilliant science and innovative medicines that help millions of people. We work across the entire value chain, designing and delivering active ingredients, formulations and devices required to support new medicines – from supplies for use in early toxicology studies and clinical trials to developing the technology to ensure drugs can be scaled up for commercial manufacture.
At Global Product Development (GPD) in Gothenburg, a sub-division of PT&D, we focus on the fields of Oral Controlled Release Drug products and Immediate Release Drug Products. You will join a vibrant team that is working on the next generation of medicines and play a key role in the development of new medicinal products.
We are currently looking for a Senior Scientist for PAT in our Product and Process Control group to strengthen our capabilities in the development and implementation of enhanced control strategies using the newest technologies to our late phase portfolio. If you have a solid scientific foundation in this domain and the aspiration to grow into an expert, this role offers an excellent fit.
This is a consultant assignment with Randstad Life Sciences starting in February. Randstad Life Sciences is specialized in competences within Life Science. As a consultant you get a competitive salary, benefits and collective agreements. Your consultant manager ensures that you get varying and developing assignments at different companies, within different industries. At Randstad Life Sciences, your personal development is in focus, and you are offered a large network and many social activities.


Deadline 2026-01-12 - the selection process and interviews will be ongoing, so please apply as soon as possible!

Responsibilities
As a Senior Scientist, you will design, develop, and deliver high?quality enhanced control methods by applying expertise in Process Analytical Technology (PAT), chemometrics, and advanced process monitoring and control. Hands?on laboratory work will be a core part of your role.
You will collaborate with cross?functional project teams, contribute to regulatory documentation, and support digital initiatives that implement innovative monitoring and control tools across continuous manufacturing platforms.
You will participate in the development, validation and technical transfer of methods and PAT tools to enable robust product control strategies across Operations. You will also champion a future?focused, innovative mindset, advancing data science, predictive modelling and simulation, and artificial intelligence to drive digitally oriented approaches.

Qualifications
Essential for the role:
BSc, MSc or equivalent in a relevant discipline (chemistry, pharmacy, engineering etc.) with experience in the use of PAT in the Pharmaceutical or Chemical industries and/or postgraduate experience in Academia with a PAT industrial focus.
A strong understanding of key PAT (e.g., NIR, Raman and microwave spectroscopy)
PAT method development experience, implementation and use of multi-variate data analysis/ Chemometrics (MVDA, PCA, PLS) in common software platforms (SIMCA, Python, MATLAB, PLS Toolbox etc.)
Ability to document and present your work concisely and comprehensibly
Strong collaboration, communication, and leadership skills
An understanding of the principles and management of Safety, Health & Environment (SHE)

Desirable for the role:
Demonstrated experience of ensuring compliance with operational requirements (GMP, GAMP, Process Safety, Data integrity, Change Control)
Experience of developing control strategies for pharmaceutical commercial manufacturing processes
Basic scripting skills (e.g. Python, Matlab, R)
Experience with digital tools supporting enhanced control strategies (DCS, PAT management system, APC, Multivariate monitoring platform)
Knowledge of pharmaceutical process equipment/technology for continuous processes


About the company

Randstad
At Randstad, we see the possible in people. With business all over Sweden and in all areas of expertise, we help people find work that feels good, where they get the opportunity to develop and realize their true potential.
With close to 600 000 employees in 38 countries, Randstad is the global leader in the HR services industry. Our mission is to become the world’s most valued working life partner. By combining our passion for people with the power of today’s technology, we support people and organizations in realizing their true potential. We call it Human Forward. Visa mindre

Job description
Research Scientist Biosamples, Biobank Scientist
AstraZeneca is a major international healthcare business engaged in the research, development, manufacture and marketing of prescription pharmaceuticals and the supply of healthcare services. However, as a company we are more than one of the world's leading pharmaceutical companies, we are proud to have a unique workplace culture that inspires innovation and collaboration. AstraZeneca employees are empowered to express diverse perspectives - and are made to feel valued, energized and rewarded for their ideas and creativity.
The arena:
Biobank scientists are responsible for the storage and timely supply of human biological samples (HBS) to AZ research projects. HBS are received from e.g. clinical studies or academic collaborations, stored in local biobanks and distributed to projects. The group primarily supports the Sweden Region but partners with other Biobank groups within AZ globally to provide efficient support across AZ and our partner organisations.
The Biobank group works collaboratively to provide support within agreed service levels with a strong focus on our customers. We strive hard to understand what fits their needs best and to add value through our services. With an increased focus on the value and use of biobank samples we actively seek ways to improve our process or exploit new technology to build a cutting-edge facility.
AstraZeneca is one of the world’s most exciting bio-pharmaceutical companies. From scientists to sales, lab techs to legal, we’re on a mission to turn ideas into life-changing medicines that improve patients’ lives and benefit society. We need great people who share our passion for science and have the drive and determination to meet the unmet needs of patients around the world.
This is a consultant assignment with Randstad Life Sciences. Randstad Life Sciences is specialized in competences within Life Science. As a consultant you get a competitive salary, benefits and collective agreements. Your consultant manager ensures that you get varying and developing assignments at different companies, within different industries. At Randstad Life Sciences, your personal development is in focus, and you are offered a large network and many social activities.
Deadline 2024-09-05 - the selection process and interviews will be ongoing. For more information: Please contact Malin Fridholm, [email protected]
Please note that applications sent through email will not be processed and deleted due to GDPR.

Responsibilities
Tasks and responsibilities/The role:
We are currently recruiting for a Biobank Scientist in the AZ Gothenburg Biobank group within the global Precision Medicine and Biosamples organization. This position will provide the opportunity to work in a dynamic and enthusiastic environment whilst supplying a critical service to drug discovery projects. The work is highly collaborative with the team having a collective responsibility for the overall delivery.
The role is focused on supporting drug discovery projects within R&D Gothenburg by maintaining high quality handling and storage of HBS and support projects with requested samples in a timely manner.
As a Biobank Research Scientist you will be expected to:
Work as part of the team rotating between the following typical tasks
Receive and register incoming HBS
Process requests for HBS to customers, including using automated liquid handler
Manage customer orders using specialized informatics systems as well as databases
Respond to customer queries via mail or telephone
Partner with Biobank groups globally as well as internal and external customers

?The group has a strong emphasis on continuous improvement which takes the form of individual and group projects within the team, the department and across Biobank groups within AZ.
The biobank team is a highly collaborative group working to tight delivery schedules so the ability to be comfortable working at a fast pace with a goal orientated and team focussed attitude is essential. Excellent communication skills with a proactive and service minded approach is key.
Work closely with other groups in the organization
Act upon day-to-day issues that occur whilst processing HBS samples to ensure continuous improvement
Identify initiatives to improve efficiency or quality.


Qualifications
Essential for the role:
University degree in a Bioscience discipline and previous experience of laboratory work handling biological samples.
Previous knowledge and experience (1 year) of biobanking is highly desirable.
Experience of working with various IT solutions, including extensive knowledge of Excel, LIMS systems and database usage, is also a clear advantage.
Experience of automated liquid handling is advantageous.
Good analytical and problem-solving skills involving large and complex datasets is desirable.
Excellent English, both spoken and written



Soft skills:
Ability to plan, perform and evaluate experiments to investigate improvement possibilities in a process.
Knowledge of the regulatory framework of biological samples.
Interest in logistics and developing processes through customer interactions and technology awareness.
Drive and enthusiasm to solve the root cause of problems and not only overcome the presenting problem.
Thrive on working in a committed team and gain satisfaction from the overall performance of the group


About the company

Randstad
At Randstad, we see the possible in people. With business all over Sweden and in all areas of expertise, we help people find work that feels good, where they get the opportunity to develop and realize their true potential.
With close to 600 000 employees in 38 countries, Randstad is the global leader in the HR services industry. Our mission is to become the world’s most valued working life partner. By combining our passion for people with the power of today’s technology, we support people and organizations in realizing their true potential. We call it Human Forward. Visa mindre

Job description
Scientist in Genome Medicines


We are developing state-of-the-art technologies and models to advance gene and cell therapy approaches. AstraZeneca’s Genome Editing Team in Gothenburg, Sweden, is now looking for a passionate Scientist to innovate in the field of Therapeutic Genome Editing. If you are looking for a fast-paced environment where your scientific insights can translate into meaningful impacts on patient lives, this is the position for you!
Meet us:
As a Scientist in the Genome Editing Team, you will join an international group of energetic researchers of various backgrounds who are excited about science and challenge its dogmas. We create a supportive and inclusive environment, and a fun atmosphere for everyone independent of their preferences, experiences and beliefs. Our work focuses on basic yet translational research that is designed to reach the clinics. Especially, we are passionate about modifying genomes at will for therapeutic purposes.
Our successful candidate needs the ability to communicate, interact and collaborate with other team members, as well as across our AZ global functions and fields. Alongside this, our ideal candidate enjoys working in an innovative, proactive, forward-thinking, project-focused and goal-oriented way and shares our excitement about the latest gene-editing techniques.
Why AstraZeneca?
We are working towards treating, preventing, modifying and even curing some of the world’s most complex diseases. Here we have the potential to grow our pipeline and positively impact the lives of billions of patients around the world.


This is a consulting assignment with Randstad Life Sciences. Randstad Life Sciences is specialized in competences within Life Science. As a consultant with us, you get a competitive salary, benefits and collective agreements. Your consultant manager is always there for you and ensures that you get varying and developing assignments at different companies, within different industries. At Randstad Life Sciences, your personal development is in focus, and you are offered a large network and many social activities.
Deadline: 2024-06-10, selection and interviews will be ongoing. For more information: Please contact Malin Fridholm, [email protected]

Responsibilities
As a Scientist in the Genome Editing Team, you will join an international group of energetic researchers of various backgrounds who are excited about science and challenge its dogmas. We create a supportive and inclusive environment, and a fun atmosphere for everyone independent of their preferences, experiences and beliefs. Our work focuses on basic yet translational research that is designed to reach the clinics. Especially, we are passionate about modifying genomes at will for therapeutic purposes.

Qualifications
Essential for the role:
The detailed knowledge of Therapeutic Genome Editing – literature, technologies, competitive landscape
Multidisciplinary laboratory experience (minimum 3 years hands-on work, after your latest degree) and meticulous scientific knowledge?in cell biology, molecular biology and genetics
Cell culture work and cell biology (genome engineering, immunofluorescence, FACS)
Molecular biology (DNA extraction, PCR, Amplicon-sequencing, Western blot)


About the company

Randstad
At Randstad, we see the possible in people. With business all over Sweden and in all areas of expertise, we help people find work that feels good, where they get the opportunity to develop and realize their true potential. With close to 600 000 employees in 38 countries, Randstad is the global leader in the HR services industry. Our mission is to become the world’s most valued working life partner. By combining our passion for people with the power of today’s technology, we support people and organizations in realizing their true potential. We call it Human Forward. Visa mindre

Job description
Here at AstraZeneca, we are working towards turning novel state-of-art technologies into effective and safe medicines for severe genetic disease. Do you want to be part of this effort? Welcome to join our exciting journey!


As our new Senior Research Scientist, you will be a part of the Therapeutic Editing team in the Department of Genome Engineering. The role is based in Gothenburg, Sweden, where you will join an international team that develops novel genome engineering technologies and applies these technologies for generation of therapeutic agents. We provide a stimulating environment for innovation and translational application of genome engineering tools, to turn them into effective and safe medicines.


We continually push the boundaries of science to deliver medicines that treat diseases across our main therapy areas. We expand the limits of scientific research to better understand diseases and to discover new life-changing treatments for them.


What you will do:


You will bring your expertise in molecular biology or screening sciences to develop novel genome editing approaches that can potentially lead to therapies. You will be a key member in cross-functional therapeutic editing project teams with various backgrounds and expertise, where you will be responsible from establishing screening capabilities and running the screens for therapeutic editing projects.




Accountabilities will include screening and optimization of genome engineering technologies to facilitate effective gene editing in target cell & tissue types, analyzing gene editing outcomes, documenting, interpreting, and communicating results to appropriate partners. You will collaborate with other functions to develop and test novel CRISPR delivery strategies – and to develop high throughput next generation sequencing approaches to analyze gene editing outcomes.


We also believe that our new colleague is a person who thinks outside the box and find innovative approaches to scientific problems. You hold enthusiasm and curiosity towards scientific questions and learning new skills. You can work in an independent and goal-oriented way, but you also enjoy team work and have the ability to communicate - collaborate in a global setting with cross-functional groups.


Why AstraZeneca?


If you are passionate about translating scientific advances into real next generation medicines, AstraZeneca is the right place for you. Join the team for unlocking the power of what science can do. You have the potential to grow yourself, our pipeline, and positively impact the lives of billions of patients around the world.


What’s next? If this sounds like a good opportunity to you – welcome to apply!


This is a consultant assignment with Randstad Life Sciences. Randstad Life Sciences is specialized in competences within Life Science. As a consultant you get a competitive salary, benefits and collective agreements. Your consultant manager ensures that you get varying and developing assignments at different companies, within different industries. At Randstad Life Sciences, your personal development is in focus, and you are offered a large network and many social activities.


Deadline 2024-08-15- - the selection process and interviews will be ongoing
For more information: Please contact Malin Fridholm, [email protected].
Please note that applications sent through email will not be processed and deleted due to GDPR.

Responsibilities
What you will do:


You will bring your expertise in molecular biology or screening sciences to develop novel genome editing approaches that can potentially lead to therapies. You will be a key member in cross-functional therapeutic editing project teams with various backgrounds and expertise, where you will be responsible from establishing screening capabilities and running the screens for therapeutic editing projects.


Accountabilities will include screening and optimization of genome engineering technologies to facilitate effective gene editing in target cell & tissue types, analyzing gene editing outcomes, documenting, interpreting, and communicating results to appropriate partners. You will collaborate with other functions to develop and test novel CRISPR delivery strategies – and to develop high throughput next generation sequencing approaches to analyze gene editing outcomes.

Qualifications
Essential for the role:


PhD degree?in molecular/cell biology, genetics, screening sciences or relevant areas
Molecular or cell biology background and relevant hands-on skills
Expertise in DNA damage and repair
Expertise in cellular assays, such as genetic manipulation and evaluating genetic & functional outcomes using state-of-art tools including next generation sequencing, qPCR/RNA-seq etc.



Desirable for the role:


Experience with cell-based high throughput screening methodologies
Experience in advanced cellular models such as iPS cells and differentiation
Solid understanding of genome engineering
Experience in flow cytometry/FACS


About the company

Randstad
At Randstad, we see the possible in people. With business all over Sweden and in all areas of expertise, we help people find work that feels good, where they get the opportunity to develop and realize their true potential. With close to 600 000 employees in 38 countries, Randstad is the global leader in the HR services industry. Our mission is to become the world’s most valued working life partner. By combining our passion for people with the power of today’s technology, we support people and organizations in realizing their true potential. We call it Human Forward. Visa mindre

Job description
AstraZeneca is a major international healthcare business engaged in the research, development, manufacture and marketing of prescription pharmaceuticals and the supply of healthcare services. AstraZeneca is proud to offer a unique workplace culture that inspires innovation and collaboration. Co-workers are empowered to express diverse perspectives - and are made to feel valued, energized and rewarded for their ideas and creativity.


We are currently looking for a laboratory skilled Scientist to join the Bioscience COPD IPF Department within Early Respiratory and Immunology (R&I). This role is located in Gothenburg, Sweden.
The Bioscience COPD/IPF department consist of 7 teams spread across Sweden, UK and US and our focus is primarily to progress projects within our portfolio, but it also includes work to increase our knowledge of COPD and IPF and to support target identification for new projects.


This is a consulting assignment with Randstad Life Sciences. Randstad Life Sciences is specialized in competences within Life Science. As a consultant with us, you get a competitive salary, benefits and collective agreements. Your consultant manager is always there for you and ensures that you get varying and developing assignments at different companies, within different industries. At Randstad Life Sciences, your personal development is in focus, and you are offered a large network and many social activities.

Responsibilities
What you´ll do:
As a Senior Scientist you will plan, optimise, and execute in vitro experiments as well as support analysis from both in vitro and in vivo studies to progress our drug discovery projects and generate publishable scientific insights. You are expected to actively take part in scientific discussions and to add valuable input in experiment design and data interpretation to drive projects and techniques.
This is a lab-based role where you will be involved in multiple ongoing projects with responsibility to perform experiments from various cells and tissues for both in vitro-, in vivo- and patient studies. This role will give the opportunity to support, design, develop and conduct experiments supporting the identification of new drug targets and the progression of drug discovery projects.
For this role, we are looking for someone with experience in modern cell biology and molecular analysis techniques that rapidly can become an integrated project member and deliver key data.
We will rely on you to:
• Execute in vitro/ex vivo experiments according to study plans
• Contribute to the interpretation of experimental data and play an important role in the planning of further experiments
• Effectively communicate results to other members of the project, team or to departments as required
• Be an effective team member in supporting projects to meet their objectives
• To conduct where appropriate in parallel more than one area of work to agreed timelines
• Possess a range of practical skills and demonstrate flexibility within and across teams


About randstad life sciences
Randstad Life Sciences is specialized in competencies within Life Science. As a consultant with us, you get a competitive salary, benefits, and collective agreements. Your consultant manager is always there for you and ensures that you get varying and developing assignments at different companies, within different industries. At Randstad Life Sciences, your personal development is in focus, and you are offered a large network and many activities.


Deadline: 2024-06-06, selection and interviews will be ongoing. For more information: Please contact Katan Ali, [email protected]

Qualifications
Essential requirements:
Essential for the role (requirements for the matrix in FG):
-A relevant science degree (PhD) ( e.g Molecular/Cell Biology, Pharmacy, Biotechnology)
-Practical experience running in vitro assays and cell culturing
-Relevant experimental experience in cell and molecular biology methods, immunoassays, protein and RNA analysis
-Isolation, culturing and analysis of primary cell cultures along with experience in the use of biological dose response assays is desirable. Experience in immunological methods (ELISA, MSD), protein analysis (western blot) and RNA analysis (qPCR) plus handling and evaluation of pharmacological drug substances would also be benificial.
Experience in lung research is desirible
- Excellent written and oral communication skills in English is a must


Soft skills (not for Matrix but good to know when interviewing):
You also possess great problem-solving skills. You have a positive and goal-oriented attitude, and you are a team player but are also able to take your own initiatives. You are organized and incorporate the views of others in your communication and collaboration.


AstraZeneca is one of the world’s most exciting bio-pharmaceutical companies. From scientists to sales, lab techs to legal, we’re on a mission to turn ideas into life-changing medicines that improve patients’ lives and benefit society. We need great people who share our passion for science and have the drive and determination to meet the unmet needs of patients around the world.

About the company

Randstad
At Randstad, we see the possible in people. With business all over Sweden and in all areas of expertise, we help people find work that feels good, where they get the opportunity to develop and realize their true potential. With close to 600 000 employees in 38 countries, Randstad is the global leader in the HR services industry. Our mission is to become the world’s most valued working life partner. By combining our passion for people with the power of today’s technology, we support people and organizations in realizing their true potential. We call it Human Forward. Visa mindre

Job description
Research Scientist, Biobank Scientists, AstraZeneca Gothenburg


AstraZeneca is a major international healthcare business engaged in the research, development, manufacture and marketing of prescription pharmaceuticals and the supply of healthcare services. However, as a company we are more than one of the world's leading pharmaceutical companies, we are proud to have a unique workplace culture that inspires innovation and collaboration. AstraZeneca employees are empowered to express diverse perspectives - and are made to feel valued, energized and rewarded for their ideas and creativity.


The arena:
Biobank scientists are responsible for the storage and timely supply of human biological samples (HBS) to AZ research projects. HBS are received from e.g. clinical studies or academic collaborations, stored in local biobanks and distributed to projects. The group primarily supports the Sweden Region but partners with other Biobank groups within AZ globally to provide efficient support across AZ and our partner organisations.
 The Biobank group works collaboratively to provide support within agreed service levels with a strong focus on our customers. We strive hard to understand what fits their needs best and to add value through our services. With an increased focus on the value and use of biobank samples we actively seek ways to improve our process or exploit new technology to build a cutting edge facility.


This is a consulting assignment with Randstad Life Sciences. Randstad Life Sciences is specialized in competences within Life Science. As a consultant with us, you get a competitive salary, benefits and collective agreements. Your consultant manager is always there for you and ensures that you get varying and developing assignments at different companies, within different industries. At Randstad Life Sciences, your personal development is in focus, and you are offered a large network and many social activities.

Responsibilities
Tasks and responsibilities/The role:
We are currently recruiting for a Biobank Scientist in the AZ Gothenburg Biobank group within the global Precision Medicine and Biosamples organization. This position will provide the opportunity to work in a dynamic and enthusiastic environment whilst supplying a critical service to drug discovery projects. The work is highly collaborative with the team having a collective responsibility for the overall delivery.
The role is focused on supporting drug discovery projects within R&D Gothenburg by maintaining high quality handling and storage of HBS and support projects with requested samples in a timely manner.
 
As a Biobank Research Scientist you will be expected to:
-Work as part of the team rotating between the following typical tasks
-Receive and register incoming HBS
-Process requests for HBS to customers, including using automated liquid handler
-Manage customer orders using specialized informatics systems as well as databases
-Respond to customer queries via mail or telephone
-Partner with Biobank groups globally as well as internal and external customers
-Work closely with other groups in the organization
-Act upon day-to-day issues that occur whilst processing HBS samples to ensure continuous improvement
-Identify initiatives to improve efficiency or quality.
 
The group has a strong emphasis on continuous improvement which takes the form of individual and group projects within the team, the department and across Biobank groups within AZ.


About randstad life sciences
Randstad Life Sciences is specialized in competencies within Life Science. As a consultant with us, you get a competitive salary, benefits, and collective agreements. Your consultant manager is always there for you and ensures that you get varying and developing assignments at different companies, within different industries. At Randstad Life Sciences, your personal development is in focus, and you are offered a large network and many activities.


Deadline: 2024-03-22, selection and interviews will be ongoing. For more information: Please contact Katan Ali, [email protected]

Qualifications
Essential requirements:
-University degree in a Bioscience discipline and previous experience of laboratory work handling biological samples.
-Previous knowledge and experience (?1 year) of biobanking is highly desirable.
-Experience of working with various IT solutions, including extensive knowledge of Excel, LIMS systems and database usage, is also a clear advantage.
-Experience of automated liquid handling is advantageous.
-Good analytical and problem-solving skills involving large and complex datasets is desirable
-Excellent English, both spoken and written


Key Attributes:
-Ability to plan, perform and evaluate experiments to investigate improvement possibilities in a process
-Knowledge of the drug discovery process
-Interest in logistics and developing processes through customer interactions and technology awareness
-Drive and enthusiasm to solve the root cause of problems and not only overcome the presenting problem
-Thrive on working in a committed team and gain satisfaction from the overall performance of the group


The biobank team is a highly collaborative group working to tight delivery schedules so the ability to be comfortable working at a fast pace with a goal orientated and team focussed attitude is essential. Excellent communication skills with a proactive and service minded approach is key.


AstraZeneca is one of the world’s most exciting bio-pharmaceutical companies. From scientists to sales, lab techs to legal, we’re on a mission to turn ideas into life-changing medicines that improve patients’ lives and benefit society. We need great people who share our passion for science and have the drive and determination to meet the unmet needs of patients around the world.

About the company

Kelly Services (UK) Limited Visa mindre

Job description
Associate Scientist/Operational Technologist – Drug Product Delivery


AstraZeneca is a major international healthcare business engaged in the research, development, manufacture and marketing of prescription pharmaceuticals and the supply of healthcare services. AstraZeneca is proud to offer a unique workplace culture that inspires innovation and collaboration. Co-workers are empowered to express diverse perspectives - and are made to feel valued, energized and rewarded for their ideas and creativity.


We are curious, creative, and open to new ideas and ways of working. Above all, we are passionate about science and driven to always put patients first. Join AstraZeneca and apply your expertise in a company that is following the science and turn ideas into life changing medicines. We have an exciting opportunity for a talented Drug Product Delivery (DPD) Associate Scientist/Operational Technologist to be based in Gothenburg, Sweden.


Pharmaceutical Technology and Development (PT&D) is the organization that turns brilliant science into actual medicines that help millions of people. We work across the entire value chain, designing and delivering active ingredients, formulations and devices for new medicines and providing expert technical support to all AstraZeneca’s commercial drug substances and products to ensure we successfully supply medicines to patients.
Drug Product Delivery (DPD) within PT&D is the sole internal AstraZeneca department that packs, labels and distributes investigational medicinal products to clinical trial patients. We support launched, pre-launched and products under development within all our therapeutic areas. We work in a fast-paced environment where flexibility, agility and teamwork enable us to deliver high value to clinical trials.


We are now looking for two Associate Scientists/Operational Technologists starting as soon as possible with the location Gothenburg, Sweden.


This is a consulting assignment with Randstad Life Sciences. Randstad Life Sciences is specialized in competences within Life Science. As a consultant with us, you get a competitive salary, benefits and collective agreements. Your consultant manager is always there for you and ensures that you get varying and developing assignments at different companies, within different industries. At Randstad Life Sciences, your personal development is in focus, and you are offered a large network and many social activities.

Responsibilities
The role
You will have a great opportunity to learn more about pharmaceutical development working with experienced operators. This role contributes to the packaging of drug products in development phase for clinical studies. All below activities will have an impact on the speed, quality and cost of the AZ development portfolio.
Practical hands-on work in our Good Manufacturing Practice (GMP) facilities with dedicated tasks in close collaboration and to support DPD Scientist/Senior Scientist e.g. assisting GMP operators with:
Preparation of process rooms and equipment before and after clinical manufacture
Assembly/disassembly and cleaning of equipment
Primary packing, i.e. packing of tablets/capsules in bottles (manually or automated)
Secondary packing, i.e. labeling of study material (manually or automated)
Working according to SHE (Safety Health and environment) and GMP standards

The role is intended to be used in a flexible way to resolve short term bottle necks. The role holder will not become fully qualified as a GMP operator but will be able to carry out much of the work expected from operators under supervision.


About randstad life sciences
Randstad Life Sciences is specialized in competencies within Life Science. As a consultant with us, you get a competitive salary, benefits, and collective agreements. Your consultant manager is always there for you and ensures that you get varying and developing assignments at different companies, within different industries. At Randstad Life Sciences, your personal development is in focus, and you are offered a large network and many activities.


Deadline: 2024-03-29, selection and interviews will be ongoing. For more information: Please contact Katan Ali, [email protected]

Qualifications
Preferred experience/requirements
You must have completed your studies at upper secondary school level e.g. in natural/technical sciences
It is essential that you follow written procedures carefully and document executed tasks. GMP knowledge is desirable
Interest in technique and manufacturing equipment and practical hands-on work is desirable
You need to be flexible (temporary positions) with good team working skills.
Good knowledge of oral and written English is a requirement

AstraZeneca is one of the world’s most exciting bio-pharmaceutical companies. From scientists to sales, lab techs to legal, we’re on a mission to turn ideas into life-changing medicines that improve patients’ lives and benefit society. We need great people who share our passion for science and have the drive and determination to meet the unmet needs of patients around the world.

About the company

Kelly Services (UK) Limited Visa mindre

Job description
Curating data for machine learning approaches to predict recombinant protein expression

Thesis project: 30 credits
Student location: AstraZeneca, Gothenburg, Sweden
Start: January 2024


Are you a master student with a hunger for science and eager to be involved in a project where we push the boundaries of science? Are you a student with a diverse background in biotechnology and bioinformatics/multivariate data analysis/machine learning. Do you like to combine wetlab work in protein production expression screening with data curation and analysis to generate models to predict protein expression. Are you looking for an inspiring master thesis project starting in the spring 2024? Then this project at the Discovery Biology Department at AstraZeneca could be interesting to You!


A fundamental step in drug discovery and biomedical research is the generation of large quantities of high-quality proteins, which are used for multiple applications including assay development, bioassay screening, and structural biology. However, producing and delivering such proteins during the early phases of drug discovery is often a rate-limiting step. The current processes to design protein constructs are labour-intensive, requiring multiple rounds of optimization via trial and error, making the overall process time-consuming and costly.


The project aims to support ongoing efforts within the department and in collaboration with the Data Science and Quantitative Biology department to develop methodologies to predict protein expression.


At AstraZeneca, all of our employees make a difference to patients’ lives every day. We operate in more than 100 countries around the world and are one of Sweden’s most important export companies.


With more than 2,400 employees from 50 countries, the vibrant Gothenburg site helps to support the entire life-cycle of AstraZeneca medicines, from drug discovery and clinical trials, to global commercialisation and product maintenance. Gothenburg is one of AstraZeneca’s three strategic, global R&D centres, alongside Cambridge and Gaithersburg, and plays a central role in our mission to deliver life-changing medicines to patients.


Application


Randstad Life Sciences is collaborating with AstraZeneca in this recruitment process. Please send your application in English and we only accept applications through Randstad’s website.


Deadline for application: 2023-10-22, selection and interviews will be ongoing. The position may be filled before the last day of application, therefore, apply as soon as possible.


All chosen candidates need to pass a background check and an alcohol and drug test before starting the project.



Responsibilities
Curating external recombinant protein expression datasets. Calibrating external datasets together with internal datasets. Work with a data science postdoc to further develop the model. Use the current and improved models to predict protein construct design and perform proof-of-concept wetlab work. The wetlab work will involve E. coli protein expression, small scale purification and analysis.



Qualifications


Understanding of recombinant protein expression.
Understanding of biological sequence modelling with a focus on protein sequence analysis and protein construct design
Proficiency in programming (Python and/or R) 
 Highly motivated, having a scientific mindset and can easily comprehend and apply ideas from the literature
Ability to watch & learn, and then perform experiments on your own, with some guidance
 Excellent attention to detail and good organizational skills
 Written and oral communication skills in English.




About the company
If you’re inspired by the possibilities of science to make a difference and ready to discover what you can do – join us! 


At AstraZeneca we are guided in our work by a strong set of values, and we’re resetting expectations of what a bio-pharmaceutical company can be. By truly following the science, we pioneer new methods, new thinking and bring unexpected teams together. From scientists to sales, lab techs to legal, we’re on a mission to turn ideas into life-changing medicines that transform lives. We need great people who share our passion for science and have the drive and determination to meet the unmet needs of patients around the world. If you’re swift to action, confident to lead, willing to collaborate, and curious about what science can do, then you’re our kind of person.


 AstraZeneca is an equal opportunity employer. AstraZeneca will consider all qualified applicants for employment without discrimination on grounds of disability, sex or sexual orientation, pregnancy or maternity leave status, race or national or ethnic origin, age, religion or belief, gender identity or re-assignment, marital or civil partnership status, protected veteran status (if applicable) or any other characteristic protected by law. AstraZeneca only employs individuals with the right to work in the country/ies where the role is advertised. Visa mindre

Job description
Investigation of the molecular mechanisms of cardiotoxicity utilizing novel cardiovascular in vitro models and technology platforms  


If you’re inspired by the possibilities of science to make a difference and ready to discover what you can do – join us!


Thesis type: 60 credits
Project start: September 2023
Student location: On Site, Gothenburg Sweden



Damage to the cardiovascular system either structural or functional in nature by drugs (drug-induced cardiotoxicity) is an important concern during drug development. There is an unmet need to identify potential factors and gain molecular understanding of mechanisms underlying drug-induced cardiotoxicity. Within the cardiovascular safety team at AstraZeneca, we see the potential of integrating improved physiologically relevant cell models that more accurately recapitulate the patient population (i.e. disease background), with omics approaches to help more accurately predict drug-induced toxicology early in drug discovery, enabling optimal compounds to progress into clinical development.  


This role will be within a global R&D department, Clinical Pharmacology and Safety Sciences, supporting all AZ therapy areas from early stage to late stage drug discovery to bring safe and efficacious medicines to patients.


At AstraZeneca, all of our employees make a difference to patients’ lives every day. We operate in more than 100 countries around the world and are one of Sweden’s most important export companies.


With more than 2,400 employees from 50 countries, the vibrant Gothenburg site helps to support the entire life-cycle of AstraZeneca medicines, from drug discovery and clinical trials, to global commercialisation and product maintenance. Gothenburg is one of AstraZeneca’s three strategic, global R&D centres, alongside Cambridge and Gaithersburg, and plays a central role in our mission to deliver life-changing medicines to patients.


Randstad Life Sciences is collaborating with AstraZeneca in this recruitment process. Please send your application in English and we only accept applications through Randstad’s website.


Deadline for application: 2023-04-16, selection and interviews will be ongoing. The position may be filled before the last day of application, therefore, apply as soon as possible.


For us, it is important that all competence and skills in the labor market are utilized. We welcome all applicants and strive for diversity.



Responsibilities
In this graduate role, you will generate advanced cardiovascular models (healthy or diseased) representative of the key cell types in the heart using both stem cell derived cells and primary cells, and characterize their response to drug-induced injury utilizing a variety of state-of-the-art technology platforms. You will be at the forefront of innovative medicines working with experts across global multi-disciplinary teams in the fields of cardiac biology and toxicology. From this cutting-edge work there is the potential for publication in high-impact journals and influence the future direction of the cardiovascular safety strategy within AZ.   

Qualifications
Essential Requirements 
A degree in Biological Sciences/Bioengineering
Experience working within a laboratory environment
Technically minded with enthusiasm and aptitude for tackling unfamiliar aspects of cardiovascular safety science
Proficient with aseptic mammalian cell culture
Excellent interpersonal skills

 
Desirable Requirements 
Quantitative real-time PCR 
Fluorescent microscopy
Cellular transfections


About the company
If you’re inspired by the possibilities of science to make a difference and ready to discover what you can do – join us! 


At AstraZeneca we are guided in our work by a strong set of values, and we’re resetting expectations of what a bio-pharmaceutical company can be. By truly following the science, we pioneer new methods, new thinking and bring unexpected teams together. From scientists to sales, lab techs to legal, we’re on a mission to turn ideas into life-changing medicines that transform lives. We need great people who share our passion for science and have the drive and determination to meet the unmet needs of patients around the world. If you’re swift to action, confident to lead, willing to collaborate, and curious about what science can do, then you’re our kind of person.


AstraZeneca is an equal opportunity employer. AstraZeneca will consider all qualified applicants for employment without discrimination on grounds of disability, sex or sexual orientation, pregnancy or maternity leave status, race or national or ethnic origin, age, religion or belief, gender identity or re-assignment, marital or civil partnership status, protected veteran status (if applicable) or any other characteristic protected by law. AstraZeneca only employs individuals with the right to work in the country/ies where the role is advertised. Visa mindre

Job description
Do you want to learn about early drug discovery and be part of evaluating a novel target with life changing potential?

If you’re inspired by the possibilities of science to make a difference and ready to discover what you can do – join us!


Thesis type: 30 credits
Project start: August 2023
Student location: On Site, Gothenburg Sweden



Idiopathic pulmonary fibrosis (IPF) is a progressive lung disease characterized by irreversible loss of lung function due to the formation of lung fibrosis. During the progression of IPF, lung parenchyma and architecture is destroyed, and fibrotic scar tissue is produced. This results in loss of lung compliance and compromised gas exchange which usually leads to respiratory failure and death within 3–5 years of diagnosis. There is a huge unmet need for new medicines in order to increase the life expectancy, alleviate symptoms, and improve the well-being in IPF patients.


AstraZeneca is a major international healthcare business and offer a unique workplace culture that inspires innovation and collaboration. We have a great opportunity for a thesis project in one of our Bioscience department at our vibrant R&D site in Gothenburg.

At AstraZeneca, all of our employees make a difference to patients’ lives every day. We operate in more than 100 countries around the world and are one of Sweden’s most important export companies.
 
With more than 2,400 employees from 50 countries, the vibrant Gothenburg site helps to support the entire life-cycle of AstraZeneca medicines, from drug discovery and clinical trials, to global commercialisation and product maintenance. Gothenburg is one of AstraZeneca’s three strategic, global R&D centres, alongside Cambridge and Gaithersburg, and plays a central role in our mission to deliver life-changing medicines to patients.


Randstad Life Sciences is collaborating with AstraZeneca in this recruitment process. Please send your application in English and we only accept applications through Randstad’s website.


Deadline for application: 2023-04-16, selection and interviews will be ongoing. The position may be filled before the last day of application, therefore, apply as soon as possible.


For us, it is important that all competence and skills in the labor market are utilized. We welcome all applicants and strive for diversity.




Responsibilities
In this placement, you will be part of a cross-functional team within Research and Early Development, Respiratory and Immunology (R&I), building scientific knowledge around disease-causing molecular mechanisms and identification of novel targets for treatment. Specifically, you will be investigating the role of a novel target in IPF using different 2D and 3D in vitro models.
 
Objectives and goals:
Contribute scientifically to evaluating a novel target to prevent lung fibrosis and stop disease progression in IPF by using a range of different 2D and 3D in vitro models with primary lung cells.
Acquire extensive training in fundamental molecular and cell biology techniques, including qPCR, cell imaging, Western blot and other cellular/protein assays as well as an ex vivo human lung explant model. 
Get insight in preclinical project work and drug discovery. 


Qualifications
Essential Requirements 
Good networking skills and interpersonal skills.
Interest and curiosity in molecular biology and the experimental work behind drug discovery.
Ability to work independently.
Written and oral communication skills in English.

 
Desirable Requirements 
Experience in cell culture.
Experience in molecular cell biology techniques eg. qPCR and Western blot.
Skilled in problem solving.


About the company
If you’re inspired by the possibilities of science to make a difference and ready to discover what you can do – join us! 

At AstraZeneca we are guided in our work by a strong set of values, and we’re resetting expectations of what a bio-pharmaceutical company can be. By truly following the science, we pioneer new methods, new thinking and bring unexpected teams together. From scientists to sales, lab techs to legal, we’re on a mission to turn ideas into life-changing medicines that transform lives. We need great people who share our passion for science and have the drive and determination to meet the unmet needs of patients around the world. If you’re swift to action, confident to lead, willing to collaborate, and curious about what science can do, then you’re our kind of person.

AstraZeneca is an equal opportunity employer. AstraZeneca will consider all qualified applicants for employment without discrimination on grounds of disability, sex or sexual orientation, pregnancy or maternity leave status, race or national or ethnic origin, age, religion or belief, gender identity or re-assignment, marital or civil partnership status, protected veteran status (if applicable) or any other characteristic protected by law. AstraZeneca only employs individuals with the right to work in the country/ies where the role is advertised. Visa mindre

Job description
Are you a university student looking for thesis work with start fall 2023? Are you interested in the pharmaceutical industry? Then AstraZeneca might be the one for you!

AstraZeneca offers 30 and 60 credit thesis work within different areas of the company. We are looking for motivated master students, passionate about science and willing to learn a broad range of new techniques.

Application
Randstad Life Sciences is cooperating with AstraZeneca in this recruitment process. We only handle applications sent through Randstad’s website.This is a general advertisement for thesis work at AstraZeneca Gothenburg. Specific advertisements for the thesis projects will be published during March-May. Are you interested in doing your thesis work at AstraZeneca, we recommend that you apply here already today!

All chosen candidates need to pass a background check and an alcohol and drug test before starting the project.
Deadline for application: 2023-03-17

For more information: Malin Fridholm, [email protected] or Veronika Knudsen, [email protected]

Responsibilities
AstraZeneca offers 30 and 60 credit thesis work within different areas of the company. We are looking for motivated master students, passionate about science and willing to learn a broad range of new techniques.

Qualifications
Currently enrolled as a student within a technical, scientific, IT or other relevant field
A strong interest in pharmaceuticals or the pharmaceutical industry
Open and comprehensive scientific mindset.
Written and oral communication skills in English
Ability to work collaboratively across boundaries and problem solve in the absence of complete information.


About the company
At AstraZeneca, all of our employees make a difference to patients’ lives every day. We operate in more than 100 countries around the world and are one of Sweden’s most important export companies.
 
With more than 2,400 employees from 50 countries, the vibrant Gothenburg site helps to support the entire life-cycle of AstraZeneca medicines, from drug discovery and clinical trials, to global commercialisation and product maintenance. Gothenburg is one of AstraZeneca’s three strategic, global R&D centres, alongside Cambridge and Gaithersburg, and plays a central role in our mission to deliver life-changing medicines to patients.

AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorisation and employment eligibility verification requirements. Visa mindre

Job description
At AstraZeneca we turn ideas into life changing medicines. Working here means being entrepreneurial, thinking big, and working together to make the impossible a reality. We’re focused on the potential of science to address the unmet needs of patients around the world. We commit to those areas where we think we can really change the course of medicine and bring big new ideas to life. We continuously forge partnerships that help pursue world-class medicines in new ways, combining our people’s exceptional skills with those of people from all over the globe.

If you have in-depth knowledge of health economics and payer evidence requirements and its application to pharmaceutical development in the international environment, this is an opportunity to take on a role with a world-leading pharmaceutical company.

We’re looking for a Health Economics & Payer Evidence Lead to join us in one of our Global R&D hubs to support our Respiratory & Immunology portfolio.

Responsibilities
Main duties and accountabilities:
You will have a global leadership role and be responsible for shaping and delivering the evidence required to demonstrate the value of our products to payers and health authorities. You will collaborate with Clinical Development, Medical Evidence Generation, Observational Research, and Payer Teams in designing and implementing innovative health economic and payer evidence strategies and activities for target product profiles/claims, global payer evidence plans, and market access and pricing strategies. An equally important part of your role will be to lead or influence the production of scientific evidence for robust portfolio decisions, global reimbursement dossiers and reimbursement submissions to achieve market access.

You will proactively contribute to evidence planning, predict and resolve issues that affect market access decisions, and take responsibility for detailed strategic and tactical planning and implementation of payer evidence plans. Part of your remit will involve preparing proposals for outsourced health economics projects and collaborating with local market affiliates to prepare evidence that satisfies payer needs in their markets. You’ll also represent health economics an payer evidence in cross-functional project teams to ensure that worldwide payer needs are reflected in drug development programs.

Qualifications
Essential requirements:

•Solid understanding and knowledge of the development process for new molecules in order to influence development strategies and meet payer needs.
•Understanding of diverse pricing and reimbursement processes to maximize reimbursement opportunities through appropriate and timely payer evidence generation and analytics.
•Ability to influence without authority and being a strong collaborator. Experience collaborating across more than one function and understanding how this contributes to achieving business objectives
•Leadership skills and problem solving capabilities, demonstrated by an ability to evaluate threats and opportunities for health economics strategies and modify them as appropriate
•Well-developed conceptual and integrative thinking with the capability to access internal and external resources for advice
•Ability to implement projects with a high degree of autonomy, including engaging key stakeholders.
•Ability to communicate technical material clearly in writing and oral presentations to both scientific and commercial audiences.
•Driving the publication policy to support payer needs, generate peer-reviewed scientific publications, as well as effective communication of sophisticated ideas for use with both payers and other partners.
•Interaction with health technology appraisal authorities and advisors/key external experts in preparing materials for scientific advice or reimbursement submissions
•Knowledge of international healthcare systems and their changing needs for health economic and payer evidence.

Education, Training and Experience:

•Graduate / College degree in biomedical science, business, quantitative disciplines or economics
•Formal post graduate degree in health economics or a related quantitative discipline, or substantial work experience in the discipline
•Payer launch experience at a local or global level
•Payer, Health Technology Assessment, public health, or health policy experience
•In-depth knowledge and technical capability in health economics and payer evidence needs, and its application to pharmaceutical development at an international level, especially economic modelling, evidence synthesis, clinical trial design and analyses and other analytical techniques required to support payer needs.

Application
2021-07-10, selection and interviews will be ongoing. The position may be filled before the last day of application, therefore, apply as soon as possible.

For more information: Sara Kuikka [email protected] or Linnea Öster [email protected]

About the company
Randstad Life Sciences is specialized in competences within Life Science. As a consultant with us, you get a competitive salary, benefits and collective agreements. Your consultant manager is always there for you and ensures that you get varying and developing assignments at different companies, within different industries. At Randstad Life Sciences, your personal development is in focus, and you are offered a large network and many social activities.

Randstad Life Sciences is part of Randstad, the world leader in recruitment and consulting with operations in 38 countries. With this global network, in combination with our strong local foundation, we can offer a wide range of varied and developing assignments and jobs for you who are a specialist in life science. Our mission is to help you reach your true potential with your career in focus! Visa mindre

Job description
Thesis work: Curating data for machine learning approaches to predict recombinant protein expression

Are you a master student with a hunger for science and eager to be involved in a project where we push the boundaries of science? Are you a student with a diverse background in biotechnology and bioinformatics/multivariate data analysis/machine learning. Do you like to combine wetlab work in protein production expression screening with data curation and analysis to generate models to predict protein expression. Are you looking for an inspiring master thesis project starting in the spring 2023? Then this project at the Discovery Biology Department at AstraZeneca could be interesting to You!

Thesis project: 30 credits
Student location: AstraZeneca, Gothenburg, Sweden
Start: January 2023

A fundamental step in drug discovery and biomedical research is the generation of large quantities of high-quality proteins, which are used for multiple applications including assay development, bioassay screening, and structural biology. However, producing and delivering such proteins during the early phases of drug discovery is often a rate-limiting step. The current processes to design protein constructs are labour-intensive, requiring multiple rounds of optimization via trial and error, making the overall process time-consuming and costly.

The project aims to support ongoing efforts within the department and in collaboration with the Data Science and Quantitative Biology department to develop methodologies to predict protein expression.



Responsibilities
Curating external recombinant protein expression datasets. Calibrating external datasets together with internal datasets. Work with a data science postdoc to further develop the model. Use the current and improved models to predict protein construct design and perform proof-of-concept wetlab work. The wetlab work will involve E. coli protein expression, small scale purification and analysis.

Qualifications
Understanding of recombinant protein expression.
 Understanding of biological sequence modelling with a focus on protein sequence analysis and protein construct design
Proficiency in programming (Python and/or R) 
Highly motivated, having a scientific mindset and can easily comprehend and apply ideas from the literature
Ability to watch & learn, and then perform experiments on your own, with some guidance
Excellent attention to detail and good organizational skills
Written and oral communication skills in English.




About the company
If you’re inspired by the possibilities of science to make a difference and ready to discover what you can do – join us! 

At AstraZeneca we are guided in our work by a strong set of values, and we’re resetting expectations of what a bio-pharmaceutical company can be. By truly following the science, we pioneer new methods, new thinking and bring unexpected teams together. From scientists to sales, lab techs to legal, we’re on a mission to turn ideas into life-changing medicines that transform lives. We need great people who share our passion for science and have the drive and determination to meet the unmet needs of patients around the world. If you’re swift to action, confident to lead, willing to collaborate, and curious about what science can do, then you’re our kind of person.

AstraZeneca is an equal opportunity employer. AstraZeneca will consider all qualified applicants for employment without discrimination on grounds of disability, sex or sexual orientation, pregnancy or maternity leave status, race or national or ethnic origin, age, religion or belief, gender identity or re-assignment, marital or civil partnership status, protected veteran status (if applicable) or any other characteristic protected by law. AstraZeneca only employs individuals with the right to work in the country/ies where the role is advertised. Visa mindre

Mechanistic Biology & Profiling - 5d DMTA

Hays Specialist Recruitment is now looking to recruit a Senior Research Scientist to join the Mechanistic Biology & Profiling team for 5-month contract assignment at AstraZeneca in Gothenburg.

At AstraZeneca we win through science, it's at the heart of our every success. That science is only possible when we work together - we'll always make sure you're clear about how your role is connected to our wider mission to show what science can do.

We are seeking a highly motivated and scientifically curious scientist to join Mechanistic Biology & Profiling as a Senior Research Scientist. You will have the opportunity to utilize your scientific capabilities to contribute to the progression of key drug discovery programs in a highly collaborative environment. The position will be located at our vibrant R&D site in Gothenburg, Sweden. You will apply proven biochemistry and cell biology expertise for profiling of the effects of compound treatment in in vitro biochemical and cellular assays.

In this position, you will join a department whose remit is to support our BioPharmaceuticals drug discovery projects globally with early DMPK assessment, SAR profiling and detailed mechanism of action data. We offer a highly rewarding scientific environment and strong team working ethics. Mechanistic Biology & Profiling (MBP) is a part of Discovery Sciences - a multidisciplinary department which drives early drug discovery across AstraZeneca's global Research and Development portfolio.

Main Duties and Responsibilities:
This is a lab-based role focused on generating in vitro pharmacology data within a 5 day turn-around time, to support drug discovery projects globally. The delivery of frequent high-quality data is critical for the chemistry optimization process and key to drive the progression of projects. You will be an experienced lab-based scientist, able to interact across a broad range of therapeutic projects and global initiatives within Discovery Sciences. The scientist will, together with the team, be responsible for running several biochemical and cell-based assays using a wide range of techniques, as well as analyzing and reporting complex data within short timelines. Liquid handling automation and various software tools are used in the screening process and problem-solving/ optimization is required on a daily basis. You will also be expected to drive technical innovation, including the identification and development of innovative processes and workflows to deliver high quality data efficiently.

Essential Requirements:

* Ph.D. in Pharmacology, Biochemistry or a related discipline or a BSc/MSc degree with significant proven experience, preferably in the Pharmaceutical or Biotechnology industry
* Extensive experience in biochemical and cellular biology techniques, including qPCR, applied to physiologically relevant cellular assays.
* Excellent communication and collaborative skills and an ability to operate effectively in a multi-disciplinary research environment and team
* Independent analysis and evaluation of complex data and delivery of data to agreed timelines
* First-rate decision-making skills, coupled with tenacity to see decisions through, even in situations of ambiguity
* Scientific visibility and leadership through project contributions and external publications

Desirable Experiences and Abilities:

* Compound profiling in a screening environment using microtiter plates and automation
* Expertise in the design, development and validation of biochemical/cellular assays for compound profiling
* Practical knowledge of several technology platforms including Imaging and LC-MS
* Experience with additional technologies for quantifying levels and turn-over of nucleic acids in cells
* Proven ability in providing technical leadership and guidance to others
* Track record of identifying and adopting scientific and technical advances
* Excellent problem-solving skills not limited to own area of expertise Visa mindre

Job description
Curious chemistry student with passion for lab work
Would you like to work with organic synthesis applied to peptides? We are looking for a curious person with passion for chemistry that like to try out ideas in the lab. 


Thesis work 30 credits
AstraZeneca is looking for a curious chemistry student with passion for lab work for a 30 credits thesis project. The work will be unpaid but in the end the student will receive a gratuity of 20,000 SEK when the thesis is approved.

Medicinal Chemistry, RIA, Gothenburg
AstraZeneca is a major pharmaceutical company in the Gothenburg region. The work will be performed in the New Modality Group at Medicinal Chemistry within the Early Respiratory, Inflammation and Autoimmunity (RIA) disease area. Our group works with state-of-the-art synthesis of oligonucleotides and peptides and has got eight permanent members.

Responsibilities
AstraZeneca is seeking a person who would like to help them expand their toolbox of linkers for mono- and bicyclic peptides. This will include linker synthesis and application of them to peptides to see if it is possible to form the cycles envisioned. The work will be performed on non-project related compounds so as to enable disclosure and publication later on.


The work will be lab oriented and AstraZeneca's labs are well-equipped in terms of synthesis machines and fume hoods. You will be working with techniques such as solid phase peptide synthesis, chromatography, and for analysis NMR spectroscopy and LCMS will be used. A great emphasis will be put on thorough documentation of the work. Collaboration and sharing of experiences and knowledge is a key element within our group.

Qualifications
Essential Requirements
Experience of lab based practical organic chemistry
Collaborative and open personality – a good team player 
Familiar with drawing and interpreting atom based chemical structures on a computer (not just letter codes and acronyms)
Experience of NMR spectroscopy
Experience of purification of organic compounds (crystallization, flash chromatography, HPLC etc)



Desirable Requirements 
Experience of peptide chemistry (preferably SPPS)
Experience of LCMS


Application
Deadline for application: 2019-11-17, selection and interviews will be ongoing. The position may be filled before the last day of application, therefore, apply as soon as possible.

 For more information: Kerstin Karlsson [email protected] or Eleonor Ehrman +4673-343 41 09.


Key terms: monocyclic & bicyclic linker, organic synthesis, peptide synthesis, cyclization, purification. Curious chemistry student with passion for lab work

About the company
At AstraZeneca we turn ideas into life changing medicines and strive to continuously meet the unmet needs of patients worldwide. Working here means being entrepreneurial, thinking big and working together to make the impossible a reality. If you are swift to action, confident to lead, willing to collaborate, and curious about what science can do, then you’re our kind of person.




AstraZeneca is an equal opportunity employer. AstraZeneca will consider all qualified applicants for employment without discrimination on grounds of disability, sex or sexual orientation, pregnancy or maternity leave status, race or national or ethnic origin, age, religion or belief, gender identity or re-assignment, marital or civil partnership status, protected veteran status (if applicable) or any other characteristic protected by law. AstraZeneca only employs individuals with the right to work in the country/ies where the role is advertised. Visa mindre

Job description
Master student project on PROTACs assay development at AstraZeneca, 60 credits
 
At AstraZeneca we turn ideas into life changing medicines and strive to continuously meet the unmet needs of patients worldwide. Working here means being entrepreneurial, thinking big and working together to make the impossible a reality. If you are swift to action, confident to lead, willing to collaborate, and curious about what science can do, then you’re our kind of person.
 
Introduction 
We have an attractive opening for a master student to join our In vitro Biochemical Assays team, for developing high throughput assays for studying PROTAC-mediated protein degradation. PROTACs (Proteolysis targeting chimera) have emerged as an important new modality in drug discovery with the potential to deliver the next generation of medcines. We are interested to explore novel in vitro assays for understanding the mechanism of PROTAC-mediated protein degradation. 
 
AstraZeneca is a global, innovation-driven biopharmaceutical business that focuses on the discovery, development and commercialisation of prescription medicines for some of the world’s most serious diseases. Our Discovery Sciences team operates from truly state-of-the-art centre in Sweden. You’ll work with some of the most knowledgeable technological experts in the industry, all collaborating on high-profile drug discovery projects. We’re also early adopters of new technologies to support innovation, including CRISPR, genome editing techniques, PROTACs, transcriptomics and next-generation sequencing.

Responsibilities
On a daily basis you will work in the In vitro Biochemical Assays team with colleges/experts working on developing high throughput biochemical assays using state-of-the-art technologies to support drug discovery projects. You will be developing a project integrated in our current research activities benefiting from daily support from an experienced supervisor. 
 
In this project you will learn about the new concept of PROTAC (Proteolysis targeting chimera) modality of medicine, and have the opportunity to explore world-leading science and develop different in vitro high throughput assays for studying the mechanism of PROTAC-mediated protein degradation. During this period you will gain extensive experience in developing high throughput in vitro  assays to study the mechanism of PROTACs. You will gain practical independency in techniques/skills such as experimental design, cell culturing, Western blotting, advanced assay technologies such as TR-FRET, NanoBBRET and Nano-Glo assays, high throughput assay development, assay validation tools, and thesis writng. You will be independently conducting laboratory work, analysing the data collected and organizing it into scientific presentations to your peers, and you will have the opportunity to actively and critically participate in the development of the project. 

Qualifications
Essential
A bachelor in biological sciences with a strong cell biology or biochemical focus.
Excellent organizational, communication and interpersonal skills, combined with the ability to work collaboratively across boundaries and problem solve in the absence of complete information.
Excellent communication skills in English (speaking, presenting and writing).

Desirable
Basic knowledge around handling mammalian cell culture
Experience working in a biochemical laboratory

 
AstraZeneca is an equal opportunity employer. AstraZeneca will consider all qualified applicants for employment without discrimination on grounds of disability, sex or sexual orientation, pregnancy or maternity leave status, race or national or ethnic origin, age, religion or belief, gender identity or re-assignment, marital or civil partnership status, protected veteran status (if applicable) or any other characteristic protected by law. AstraZeneca only employs individuals with the right to work in the country/ies where the role is advertised.

Application
Randstad Life Sciences is cooperating with AstraZeneca in this recruitment process. We only accept applications through Randstad's website.
 
Deadline for application: 2020-03-31, selection and interviews will be ongoing. The position may be filled before the last day of application, therefore, apply as soon as possible.

 For more information: Kerstin Karlsson [email protected] or Eleonor Ehrman +4673-343 41 09.

About the company
At AstraZeneca we turn ideas into life changing medicines and strive to continuously meet the unmet needs of patients worldwide. Working here means being entrepreneurial, thinking big and working together to make the impossible a reality. If you are swift to action, confident to lead, willing to collaborate, and curious about what science can do, then you’re our kind of person. Visa mindre

Job description
Thesis work: 60 credits
Identifying novel treatments for intracellular protein trafficking disorders



Cystic fibrosis and Alpha-1antitrypsin deficiency (AATD), which results from intracellular polymerization and retention of mutant alpha-1antitrypsin (AAT), are examples of protein trafficking diseases and this project is aimed at identifying simpler and safer routes to the treatment of trafficking disorders.


This is a thesis position within the transgenic mouse model group which sits within the Discovery Biology (DB) department under the Discovery Science (DS) function. Within the transgenic unit, there are 4 core scientific disciplines that aim to ensure the group is at the scientific forefront and performs world leading science and innovation. 

Responsibilities
The main focus of the role will be to perform in vitro assays to identify strategies aimed at improving the trafficking of proteins, carrying genetic mutations, performing imaging and molecular analyses to confirm the fidelity of the assays. Successful strategies may be moved to an in vivo setting using transgenic mouse models of human disease.

Qualifications
Essential Requirements 
As a person you are a productive and thorough co-worker and team-player being very well organised and focussed on delivery of high quality on time
Studies performed are conducted with quality and dedication
Open and comprehensive scientific mindset



Desirable Requirements
Experience of standard molecular and cell biology techniques
Experience of in vitro work such as cell culturing
Experience of in vivo experience of mouse models would be an advantage


Application
Deadline for application: 2019-11-17, selection and interviews will be ongoing. The position may be filled before the last day of application, therefore, apply as soon as possible.

 For more information: Kerstin Karlsson [email protected] or Eleonor Ehrman +4673-343 41 09.

About the company
At AstraZeneca we turn ideas into life changing medicines and strive to continuously meet the unmet needs of patients worldwide. Working here means being entrepreneurial, thinking big and working together to make the impossible a reality. If you are swift to action, confident to lead, willing to collaborate, and curious about what science can do, then you’re our kind of person.


AstraZeneca is an equal opportunity employer. AstraZeneca will consider all qualified applicants for employment without discrimination on grounds of disability, sex or sexual orientation, pregnancy or maternity leave status, race or national or ethnic origin, age, religion or belief, gender identity or re-assignment, marital or civil partnership status, protected veteran status (if applicable) or any other characteristic protected by law. AstraZeneca only employs individuals with the right to work in the country/ies where the role is advertised. Visa mindre