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Job description
Passionate Research Scientist in Membrane Protein Science
Are you an enthusiastic scientist with skills in the field of membrane protein biology and have a passion to use your skills to contribute to the development of medicine to patients? Do you also want to join a place where our team work and collaborative atmosphere drives us forward? If yes, this might be the position for you!
Right now, we have an opportunity for a motivated Research Scientist to join the Membrane Protein Science Team at our vibrant AstraZeneca R&D site in Gothenburg, Sweden, for a one year temporary position. In this role you’ll play an important part in the Discovery Biology department within the Discovery Sciences organisation.
This is a laboratory-based research position where you will apply your skills and knowledge in protein purification and recombinant protein expression, your curiosity, combined with strong team working ethics to support our early drug discovery projects. You will join our team whose remit is to deliver impactful recombinant membrane protein reagents used to power hit-finding, lead-generation, all the way to clinical candidate validation.
This is a consultant assignment with Randstad Life Sciences with a start in November. Randstad Life Sciences is specialized in competences within Life Science. As a consultant you get a competitive salary, benefits and collective agreements. Your consultant manager ensures that you get varying and developing assignments at different companies, within different industries. At Randstad Life Sciences, your personal development is in focus, and you are offered a large network and many social activities.
Deadline 2025-10-09 - the selection process and interviews will be ongoing, so please apply as soon as possible!

Responsibilities
As a Research Scientist in the Membrane Protein Science Team you will be generating tailored membrane protein reagents to support projects in all phases of the discovery process. The role involves expression screening of constructs in eukaryotic hosts, large scale expression, and purification of recombinant membrane proteins to supply bioreagents to assay development, affinity screening and structure-based drug discovery.
You will plan and conduct experimental strategies and generate, interpret and report scientific data autonomously or in collaboration with colleagues. In addition, you will contribute to advance our capabilities in the production of recombinant membrane proteins used in early drug discovery.


Why AstraZeneca?
Join the team that follows the science unlike anywhere else. This is the place for curious minds. Dig deep into the biology of complex disease and uncover breakthroughs. With more than 2,800 employees from over than 70 countries, our vibrant Gothenburg site is a truly inspiring place to work. Here, the history and future of scientific breakthrough come together. We believe that the diversity of our people is crucial to bringing new discoveries to life.
So, what’s next? If this sounds like the job and place for you – welcome to apply!

Qualifications
Essential in the role:
Master’s in molecular biology, Biotechnology, Biochemistry or a related field, and 2 years of relevant working experience.
Expertise and proven knowledge of a wide range of methods and technologies applied to the expression, purification and characterization of membrane proteins.
Passion for experimental laboratory-based research.

We also see our new colleague as a person who thinks in an unexpected way, holds enthusiasm and curiosity towards scientific questions and learning new skills. You have great laboratory skills and the ability to make scientific judgements, as well as work in a goal-oriented way. We believe that you can work in an independent way, but you also enjoy teamwork and can communicate and collaborate in a global setting with cross-functional groups.
Desirable in the role:
Experience in recombinant expression, purification, and pharmacology of GPCRs.
Good understanding of drug discovery and how to contribute with scientific expertise within own area of expertise to drive project progression.
Expertise in cell culture for recombinant protein expression in eukaryotic cell types.


About the company

Randstad
At Randstad, we see the possible in people. With business all over Sweden and in all areas of expertise, we help people find work that feels good, where they get the opportunity to develop and realize their true potential.
With close to 600 000 employees in 38 countries, Randstad is the global leader in the HR services industry. Our mission is to become the world’s most valued working life partner. By combining our passion for people with the power of today’s technology, we support people and organizations in realizing their true potential. We call it Human Forward. Visa mindre

Job description
Senior Research Scientist - Cellular assay development for therapeutic oligo drug discovery
AstraZeneca is a major international healthcare business engaged in the research, development, manufacture and marketing of prescription pharmaceuticals and the supply of healthcare services. AstraZeneca is proud to offer a unique workplace culture that inspires innovation and collaboration. Co-workers are empowered to express diverse perspectives - and are made to feel valued, energized and rewarded for their ideas and creativity.
The arena:
We are looking for a motivated and engaged Senior Scientists to join our Oligo Cell Assay Development team at AstraZeneca in Gothenburg for a 8 months fixed term contract (maternity replacement). As a Senior Scientist in oligo cellular assay development, you will use your knowledge of cells and assay technologies to develop state-of-the-art cell-based assays for screening and profiling of potential therapeutic oligos such as antisense oligonucleotides or siRNA, with the aim to identify lead molecules. You will contribute to the progression of drug projects by bringing novel ideas and scientific strategy. You will work within Discovery Sciences, part of AstraZeneca’s BioPharmaceuticals organisation, with a focus on scientific advances in drug discovery across therapeutic areas including, respiratory and inflammation (R&I), cardiovascular, renal and metabolism (CVRM) and rare disease (Alexion).
Why AstraZeneca?
Thrive in a place where the brightest and most curious minds seamlessly come together in our inclusive environment. This is the place to go beyond discovery – we think holistically about patients and are always learning from those living with diseases.
AstraZeneca is one of the world’s most exciting bio-pharmaceutical companies. From scientists to sales, lab techs to legal, we’re on a mission to turn ideas into life-changing medicines that improve patients’ lives and benefit society. We need great people who share our passion for science and have the drive and determination to meet the unmet needs of patients around the world.
This is a consultant assignment with Randstad Life Sciences. Randstad Life Sciences is specialized in competences within Life Science. As a consultant you get a competitive salary, benefits and collective agreements. Your consultant manager ensures that you get varying and developing assignments at different companies, within different industries. At Randstad Life Sciences, your personal development is in focus, and you are offered a large network and many social activities.

Responsibilities
Tasks and responsibilities/The role:
This is an exciting opportunity for you to join us as a lab-based scientist to develop cell assays for discovery of novel oligonucleotide-based therapies. The assays you develop will be used in projects in all phases of AstraZeneca’s drug discovery pipeline. You will work closely with our colleagues in the Cell engineering and Cell banking teams, screening scientists in the oligo profiling team, and the rest of the AstraZeneca therapeutic oligo platform.
We believe that our new colleague is a highly motivated scientist with a keen interest in technological and scientific advances. Along with this we see you as a person who enjoys collaboration, who holds networking skills with experience of interacting effectively across functions and disciplines. This goes hand in hand with your problem-solving skills, great goal focus and enthusiasm for science.
You will be strongly encouraged and supported to think creatively in our dynamic environment. Here, we are free from fear of failure, free to ask the right questions, and make bold decisions.
Deadline 2024-10-10- the selection process and interviews will be ongoing, so please apply as soon as possible!
Please note that applications sent through email will not be processed and deleted due to GDPR.

Qualifications
Essential requirements:
PhD in Biology, Pharmacology, Cell biology or a related discipline or a BSc/MSc degree with significant relevant experience, preferably in the pharmaceutical or biotechnology industry.
Highly skilled in cellular biology techniques applied to develop cell-based assays.
Extensive experience in the development and application of assays for quantitative measurements of RNA transcripts.
Experience with therapeutic oligonucleotides (e.g. ASOs or siRNAs).
Experienced in working with many and diverse cell models.
First-rate analysis and decision-making skills, coupled with a tenacity to see decisions through, even in situations of ambiguity.

Desirable in the role:
Expertise in a range of cell biology techniques, including cloning, transfection methods, and gene expression knock-down (RNAi or other).
Experience in the design, development and validation of cellular assays for compound screening and /or profiling.
Cellular imaging and image analysis experience.
Experience with automation for cell assays.


About the company

Randstad
At Randstad, we see the possible in people. With business all over Sweden and in all areas of expertise, we help people find work that feels good, where they get the opportunity to develop and realize their true potential.

With close to 600 000 employees in 38 countries, Randstad is the global leader in the HR services industry. Our mission is to become the world’s most valued working life partner. By combining our passion for people with the power of today’s technology, we support people and organizations in realizing their true potential. We call it Human Forward. Visa mindre