Lediga jobb som Mikrobiolog i Mölndal

Job description
Are you an experienced hands-on in vitro biologist with excellent in vitro experimental skills? Would you like to apply your expertise in a company that follows the science and turns ideas into life changing medicines? Then this role might be the one for you!
At AstraZeneca, you will be empowered to be innovative and creative where difference is valued. We thrive in a place where the brightest and most curious minds seamlessly come together in our inclusive environment.
We now offer an exciting opportunity for a dedicated Senior Scientist to join the Bioscience Renal in vitro team within the Early Cardiovascular, Renal and Metabolism (CVRM) therapeutic area. The position is placed at AstraZeneca’s dynamic R&D site in Gothenburg, Sweden.
As Senior Scientist at the Bioscience Renal department you will be part of a vibrant team that focus on finding new treatment options to patients with renal disease. In the in vitro team we work with various pre-clinical models and different drug modalities. You will take part of both establishing new methods, using a wide array of established analysis in cell culture and advanced 3D models as well as driving new targets. At AstraZeneca, you will work together with experts from different functions and be part of project teams.
This is a consultant assignment with Randstad Life Sciences. Randstad Life Sciences is specialized in competences within Life Science. As a consultant you get a competitive salary, benefits and collective agreements. Your consultant manager ensures that you get varying and developing assignments at different companies, within different industries. At Randstad Life Sciences, your personal development is in focus, and you are offered a large network and many social activities.
Deadline 2024-03-06 - the selection process and interviews will be ongoing, so please apply as soon as possible!

Responsibilities
What you’ll do:
As a senior research scientist in the Renal in vitro team, you will independently design, plan and perform high quality in vitro experiments. You will identify and implement new methods/assays relevant for renal disease area and use a wide array of the latest technologies to analyze biological samples.
Other accountabilities:
Performing conceptual interpretation and presentation of generated data
Delivering data, reports, and regulatory documents


Qualifications
Essential for the role:
Master’s degree in biology, biotechnology, biomedicine, physiology, or medicine
Experience from in vitro work in molecular biology and other technologies such as western blot, ELISA, flow cytometry and cell imaging
Extensive expertise in cell culture-related work
Strong oral and written communication skills. English is essential, Swedish is appreciated but is not a requirement

Desirable for the role:
PhD in biology, biotechnology, biomedicine, physiology, or medicine
Proven publication record
Renal biology background
Experience from Pharmaceutical industry
Experience in cell metabolism and mitochondrial biology


About the company

Randstad
At Randstad, we see the possible in people. With business all over Sweden and in all areas of expertise, we help people find work that feels good, where they get the opportunity to develop and realize their true potential.

With close to 600 000 employees in 38 countries, Randstad is the global leader in the HR services industry. Our mission is to become the world’s most valued working life partner. By combining our passion for people with the power of today’s technology, we support people and organizations in realizing their true potential. We call it Human Forward. Visa mindre

Job description
Flow cytometry Senior Scientist in the Microphysiological Systems (MPS)
Do you have experience in flow cytometry and versatile knowledge in cell culture, and are you eager to apply your expertise in a company that accelerates innovative science to turn ideas into life-changing medicines? Join our Microphysiological Systems (MPS) team and contribute to the discovery of future preclinical models that support the development of new medications for Cardiovascular, Renal, and Metabolic (CVRM) diseases!
At AstraZeneca, we are harnessing advanced cell models, microfluidic chip technologies, multi-omics screens, flow cytometry, and mathematical modelling to achieve the next wave of breakthroughs – here we do things that have never been done before. Are you excited to contribute? Then you might be the person we are looking for!
This role is based in the MPS team at the Early CVRM department in our dynamic R&D site in Gothenburg, Sweden. The MPS team establishes and applies state-of-the-art MPS platforms to support the CVRM portfolio with emerging therapeutic area needs and new drug modalities. Our mission is to improve translatability from in vitro models to humans and accelerate drug discovery and development.
You will execute and provide input into the practical delivery of MPS studies while also serving as a flow cytometry (FACS) scientist. You will support the development, characterisation, and optimisation of advanced cell models and flow cytometry-based assays. We’ll look to you as an expert in cell and molecular biology techniques, and you will independently carry out various downstream in-vitro analytical methods.
This is a consultant assignment with Randstad Life Sciences. Randstad Life Sciences is specialized in competences within Life Science. As a consultant you get a competitive salary, benefits and collective agreements. Your consultant manager ensures that you get varying and developing assignments at different companies, within different industries. At Randstad Life Sciences, your personal development is in focus, and you are offered a large network and many social activities.

Responsibilities


Develop and execute flow cytometry-based assays for cell characterisation and functional analysis including panel design.
Take part in the design, conduct, interpretation, and reporting of studies with advanced cell models and MPS.
Carry out various downstream analyses from cell culture samples with versatile in-vitro analytical methods such as, but not limited to, ELISA, qPCR, staining, and imaging.
Join further model development activities to support drug projects with MPS and flow cytometry data for resolving mechanisms of action, target identification, and candidate drug evaluation.
Effectively communicate and collaborate across the Early CVRM department and with key stakeholders in other functions.
Why AstraZeneca?
At AstraZeneca, we follow the science to explore and innovate. We are unlocking the power of what science can do, working towards treating, preventing, modifying and even curing some of the world's most complex diseases. If you're driven by curiosity and courage, inspired by the possibility of doing things that have never been done before, this is the place for you.

Qualifications
Essential for the role:


Master’s degree + 4 years of relevant experience.
Background in Pharmacy, Biology, Biotechnology, Biochemistry, Medical Biosciences, Bioengineering, or similar.
Proficiency in flow cytometry, including assay development, troubleshooting, and data interpretation.
Strong hands-on cell culture experience.
Versatile in-vitro analytical methods (e.g., qPCR, staining and high-content imaging, plate-based assays such as ELISAs).
Independent study design, laboratory work, and data analysis.
Data visualization and statistical analysis.
Strong interpersonal and communication skills in English, both verbal and written.
Strong ability to engage and collaborate across boundaries with a problem-solving attitude and focus on delivery.

Desired for the role:


Experience in 3D cell culture, i.e., spheroids, organoids, or multicellular co-cultures.
Experience with one or more of the following cell models: liver, kidney, cardiac, pancreas, or adipose tissue.
Experience in culturing immune cells.
Handling microfluidic chips.
Workflow automation, e.g., robotic liquid handling.
Experience from the pharmaceutical industry.


About the company

Randstad
At Randstad, we see the possible in people. With business all over Sweden and in all areas of expertise, we help people find work that feels good, where they get the opportunity to develop and realize their true potential. With close to 600 000 employees in 38 countries, Randstad is the global leader in the HR services industry. Our mission is to become the world’s most valued working life partner. By combining our passion for people with the power of today’s technology, we support people and organizations in realizing their true potential. We call it Human Forward. Visa mindre

Job description
Are you an experienced scientist ready to apply your skills in a diverse and dynamic organization? If you can envision providing scientific expertise in a role that can impact patients’ lives – join us now!
At AstraZeneca, we believe in the potential of our people, and you’ll develop beyond what you thought possible. We make the most of your skills and passion by actively supporting you to see what you can achieve no matter where you start with us.
We are now looking to recruit an In Vivo Scientist with excellent laboratory skills and a drive for innovation to join the Bioscience in vivo department within the Early Respiratory and Immunology (eR&I) R&D unit located in Gothenburg, Sweden.
Respiratory and immunology are two of AstraZeneca’s main therapy areas. From a research perspective we work to understand, treat, modify, and ultimately cure respiratory disease with an emphasis on four respiratory diseases with significant unmet medical need: asthma, COPD, Idiopathic Pulmonary Fibrosis (IPF) and Chronic Cough. In addition, we also focus on immunology-driven disease areas including rheumatology, dermatology, gastrointestinal and inflammatory diseases driven by eosinophilic immune dysfunction.
The successful candidate will join a highly motivated team that works closely together with other departments focusing on target identification, drug formulation, translational science, in vitro assay development and drug metabolism/pharmacokinetics to support discovery projects and to drive exciting new research. Are you ready to join us?
This is a consultant assignment with Randstad Life Sciences starting in January. Randstad Life Sciences is specialized in competences within Life Science. As a consultant you get a competitive salary, benefits and collective agreements. Your consultant manager ensures that you get varying and developing assignments at different companies, within different industries. At Randstad Life Sciences, your personal development is in focus, and you are offered a large network and many social activities.

Responsibilities
As a vital member of our in vivo team, you will contribute to progress our drug discovery projects. Your role will be mainly lab-based in which you will be actively involved and responsible to coordinate, perform and analyze in vivo studies. While we expect you to be independent, we are also looking for someone that thrives in a team setting and contributes to the success of others.
At AstraZeneca when we see an opportunity for change, we seize it and make it happen, because any opportunity no matter how small, can be the start of something big. Delivering life-changing medicines is about being entrepreneurial - finding those moments and recognizing their potential. Join us on our journey of building a new kind of organization to reset expectations of what a bio-pharmaceutical company can be. This means we’re opening new ways to work, pioneering groundbreaking methods, and bringing unexpected teams together. Interested? Come and join our journey.
So, what’s next!
Are you already imagining yourself joining our team? Good, because we can’t wait to hear from you.
Deadline 2024-11-29 - the selection process and interviews will be ongoing, so please apply as soon as possible!
For more information: Please contact Malin Fridholm, [email protected]. Please note that applications sent through email will not be processed and deleted due to GDPR.

Qualifications
Essential for the role:
B.Sc. or M.Sc. degree in relevant subjects or equivalent level of understanding developed through experience in drug discovery or early development.
Excellent technical and experimental In vivo experience and skills, including rodent handling, drug administration and collection of biological samples. Ability to coordinate and perform respiratory disease and mechanistic models.
Valid certificates to work with live animals in Sweden.
Excellent written and oral communication skills in English.
Maintain the highest standards of animal welfare and ethical compliance and ensure integrity of generated data. Familiar with using Good Statistical Practice in animal research and applying the 3R’s (reduction, refinement, and replacement) across the full range of studies.
Good generic computer proficiency including Microsoft Office.

Desirable for the role:
Experience in basic cellular and molecular biology techniques (e.g. ELISA, western blot, FACS, Meso Scale Discovery (MSD) technology platform), and gene expression analyses (qPCR)).
Ability to interpret and analyze generated data.
Be respectful, communicate openly and show effective collaborative behavior to obtain high quality study results.
Good written and oral communication skills in Swedish and experience in writing ethical applications for animal work in Sweden.
Excellent organization skills.
Ability to incorporate the views of others in your communication.
Good understanding of pharmacology, physiology, immunology, respiratory diseases (COPD, asthma, cough, IPF) and PKPD relationships.
Scientist, Early R&I Research and Early Development, Bioscience In Vivo


About the company

Randstad
At Randstad, we see the possible in people. With business all over Sweden and in all areas of expertise, we help people find work that feels good, where they get the opportunity to develop and realize their true potential.

With close to 600 000 employees in 38 countries, Randstad is the global leader in the HR services industry. Our mission is to become the world’s most valued working life partner. By combining our passion for people with the power of today’s technology, we support people and organizations in realizing their true potential. We call it Human Forward. Visa mindre

Manufacturing Unit

Hays Life Sciences is now looking to recruit a Scientist/Senior Scientist - Microbiology, Early Product Development and Manufacture to join the Manufacturing Unit for a 1-year contract assignment at AstraZeneca in Gothenburg.

At AstraZeneca, we unlock the power of What Science Can Do. Empowered to explore, every day we work towards our ultimate aim - treating, preventing, modifying and even curing complex diseases. Be part of the team where you are empowered to follow the science!

Pharmaceutical Sciences (PharmSci) is responsible for the design and development of synthetic routes, preclinical and phase I/II formulations, encompassing both small molecules and new modalities such as mRNA and oligonucleotides, across the whole range of AstraZeneca's therapeutic areas.

Within Early Product Development and Manufacture (EPDM) in Gothenburg, Sweden, the manufacturing unit is accountable for delivering a vast portfolio of early investigational medicinal products. We have a wide range of manufacturing assets in three separate manufacturing facilities, supplying different types of clinical trial material to studies across the globe.

The role
We are now seeking a new member to join our fantastic team, based at AstraZeneca's dynamic R&D site in Gothenburg, Sweden. With employees from more than 50 countries, our Gothenburg site is a truly inspiring place to work. Within the EPDM manufacturing unit, in the GMP (Good Manufacturing Practice) arena, you will make an important contribution in delivering clinical results in the development of new medicines.

This role is focused on environmental monitoring of the multipurpose GMP facilities and support to the manufacturing within the field of microbiology/hygiene. Therefore, knowledge within microbiology is a requirement for this role. In addition, experience of GMP purified water/water for injection systems is a merit, as accountabilities within these areas are included.

What you'll do
Working in the role as Scientist/Senior Scientist in EPDM and PharmSci, you will be part of an amazing group of skilled and driven colleagues who truly embrace team spirit, who you will exchange knowledge and collaborate with on many levels in various contexts. This role provides excellent opportunities for your professional development, and possibilities to take on further accountabilities in line with your personal growth.

Your main accountabilities/responsibilities:

* Rapidly develop strong competence within relevant areas of responsibility and build credibility and ability to drive improvements and interact with stakeholders locally and globally.
* Work with practical hands-on processes in our GMP facilities, planning and performing hygiene and water sampling, and coordinate accordingly with QC Microbiology laboratory.
* Compile and evaluate microbiological results in periodic trend and review reports.
* Support with microbiological expertise in risk assessments and validation activities related to facility, equipment, and cleaning.
* Lead deviation investigations related to EM (environmental monitoring) and water result excursions, advising on corrective and preventive actions (CAPA).
* Support introduction and maintenance of new technology (EM LIMS) and sampling equipment with regards to microbiological aspects.
* Execute internal hygiene inspections and carry out basic GMP hygiene training sessions.
* Have a strong competence within documentation to be able to perform risk assessments, deviation documentation including CAPA, author SOPs, write reports and change controls, and other guidance documents in accordance with GMP quality systems.
* Monitor, secure and follow up on regulatory requirements according to GMP
* Ensure that SHE (Safety, Health and Environment) and GMP standards are upheld and ensure AZ Policies and Standards are understood and followed.
* Be entrepreneurial and drive initiatives to further improve flexibility and productivity, resulting in improved processes or increased value for our customers and patients.

Do you have the essential qualifications for these roles?
To be successful in this role, we believe that you have a MSc in Microbiology or similar, or experience of cGMP within the pharmaceutical industry in combination with knowledge within the field of microbiology. If you have previous experience in working with hygiene sampling and work with water systems, this will be an advantage.

The perfect candidate would be a Scientist/Senior Scientist with excellent collaboration, communication, and planning skills with a strong sense of responsibility, team work and delivery focus. You are able to work independently and manage a wide range of specific tasks without losing focus, and you are able to prioritize workload and adjust priorities. Strong verbal and documentation skills in English is a requirement. Visa mindre

We are looking for an experienced and driven Microbiologist, who likes new challenges and wants to be a part of the development of new products based on bacteria from the intestinal flora.
As a Microbiologist at MetaboGen, you will be an important part of our development team. You will work with anaerobic bacteria in the laboratory, with fermentation development and also with documentation during product development and early production phase.
In this role you will be based at MetaboGen's laboratory in Mölndal, Göteborg, together with the rest of the team. On occasion, you will spend time in our manufacturing plant in Eslöv.
Your main responsibilities will be
Microbiology laboratory work
Fermentation and process development work
Documentation and establishment of SOPs and related documents
Participation in meetings with the development team

Qualifications and competencies
Relevant academic degree with focus in Microbiology
Experience of microbiology work. It is an advantage if you have been working with anaerobic bacteria and in an industrial environment
Fermentation experience
Very good knowledge in English.
As a person, you are a team player with a "can do" mindset. You can work independently and take the responsibility to solve problems. In this role, it is important that you are accurate and structured.

About the company
MetaboGen is a pioneering company addressing the microbiome to understand health and disease. The company is creating breakthrough opportunities to develop novel therapeutics and next generation probiotics. Today, MetaboGen is working with several projects that will improve people's life. Our first product is in clinical phase. In 2018, the Swedish probiotic company BioGaia acquired MetaboGen and today we are a subsidiary of BioGaia with head quarter in Stockholm. Visa mindre

Job description
Are you an experienced scientist in the field of pluripotent stem cells (PSC) and neuroscience? Would you like to use your scientific skills to drive the development of stem-cell derived neural models for therapeutic development?

This might be the next challenge for you!

At AstraZeneca in Gothenburg, Sweden we have an exciting opportunity for you to join us in the Applied Stem Cell Sciences in Discovery Sciences, Biopharmaceuticals R&D, as a bench-based Research Scientist to be a key player in developing stem cell models for neuroscience applications.

The role
You will be based in Gothenburg Sweden, working alongside our stem cell scientists, disease area specialists and genome editing group. Using your strong knowledge and experience in stem cell biology, cell model development, and primary cell culture you will have the opportunity to work on in vitro assay development for neuroscience applications. This includes culture and differentiation of induced pluripotent stem cells (iPSCs), primary neuronal cultures and carrying out gene editing experiments where necessary.

The role is focused on laboratory-based activities. Your biggest impact will be through significant contributions to the practical delivery to projects in compliance with AstraZeneca corporate responsibility, policies and relevant safety standards.

It is essential to have good social and communication skills, be collaborative and a strong team player. Candidates should be able to work independently, take own initiatives and have a positive, goal oriented and problem-solving attitude.

Good organizational, data management and documentation skills are required, and you should be comfortable in presenting your results. English language is required, both spoken and in writing. 

Responsibilities




Qualifications
Key Skills and Responsibilities:
BSc/MSc/PhD degree with significant experience in Neuroscience, Developmental Biology or Cell Biology
Proven experience with human PSC biology and differentiation to neural cell types
Experience with primary neuronal cultures
Experience in developing biochemical and cell-based assays in primary and PSC-derived neurons, introducing agents by viral transduction or transfection.
Proficiency in cellular and molecular biology techniques, including qPCR, ELISA, Western blotting, Flow cytometry, routine immunofluorescence and IHC staining
Perform in vitro studies to investigate the effects of CRISPR-based gene editing on gene and protein expression and cellular readouts.
Effectively collaborate within a matrixed research team to facilitate the success of projects. Maintain complete experimental records.


The following skills are highly desirable:
Experience with CRISPR gene editing, clonal cell line generation, and NGS library prep
Expertise with liquid handling automation technologies
Experience of setting up cell based pharmacological assays


Application
Deadline: 2022-02-26 , selection and interviews will be ongoing. The position may be filled before the last day of application, therefore, apply as soon as possible.

For more information:
Please contact Jimmy Wadie [email protected]

About the company
Randstad Life Sciences is specialized in competences within Life Science. As a consultant with us, you get a competitive salary, benefits and collective agreements. Your consultant manager is always there for you and ensures that you get varying and developing assignments at different companies, within different industries. At Randstad Life Sciences, your personal development is in focus, and you are offered a large network and many activities.

Randstad Life Sciences specializes in the field of science and is part of Randstad, the world leader in recruitment and consulting with operations in 38 countries. With this global network, in combination with our strong local foundation, we can offer a wide range of varied and developing assignments and jobs for you who are a specialist in life science. Our mission is to help you reach your true potential with your career in focus! 
https://www.randstad.se/lifesciences Visa mindre

Disease Molecular Profiling - NGS & Transcriptomics team

Hays Life Sciences is now looking to recruit a Senior Scientist - NGS for High-Throughput Transcriptomics for a contract assignment until 2023-04-01 with a possibility of extension at AstraZeneca in Gothenburg.

Are you an experienced Molecular Biologist with expertise in Next Generation Sequencing (NGS)? Do you wish to apply this knowledge in a role that is connected to our wider mission to show what science can do? If yes, we might have the role for you!

We seek a talented and highly engaged Molecular Biology/NGS scientist to join the Disease Molecular Profiling - NGS & Transcriptomics team at AstraZeneca in Gothenburg, Sweden. You will contribute with applying molecular biology and NGS expertise to our drug discovery portfolio and working on cutting edge technologies within the field.

What you will do:

* Work collaboratively with scientists from our team, different therapy areas, and computational biology to apply genomic technologies to further drug discovery.
* Develop, evaluate, or implement customized NGS workflows for specific drug discovery projects.
* Plan, design, run, enhance and troubleshoot existing NGS workflows such as bulk RNA-seq (e.g. mRNA-seq, totRNA-seq, ultra-low-input) and high-throughput transcriptomics (e.g. 384-well-based methods).
* Understand and interpret data analyzed by computational biology colleagues and communicate it effectively to project partners and stakeholders.
* Keep records of all lab and technology development work and write technical reports and SOPs.
* Effectively manage timelines and deliver projects according to deadlines.

Essential for the role:

* Ph.D. degree or MSc with experience in Molecular Biology, Biotechnology, Biomedicine or in a relevant scientific discipline.
* Hands-on lab-based experience in utilizing advanced molecular biology RNA-sequencing, DNA-sequencing or Epigenetic sequencing techniques.
* This experience will cover all relevant aspects from hypothesis generation, through experimental design and execution, RNA and DNA extraction, sample and library preparation, sequencing (ideally with Illumina or Nanopore), data handling, post-sequencing QC and troubleshooting.
* Scientifically-driven scientist with attention to details and excellent critical thinking skills.

Desirable for the role:

* Background in applying a broad range of wet-lab techniques, such as mammalian cell-culture, high-throughput in-vitro drug testing, qPCR or automated liquid handling.
* Working with laboratory automation / liquid handling systems, method and technology development and optimization.
* Hands-on experience with Single Cell Transcriptomics or Spatial Transcriptomics.
* Tissue dissection, single cell dissociation, microscopy, flow cytometry/FACS
* Hands-on laboratory experience running NGS platforms (Illumina, Oxford Nanopore etc.).
* Sample Tracking by LIMS systems. Visa mindre

Job description
We are looking for a consultant for an interesting role in the COVID-19 assessment team at AstraZeneca, Gothenburg.

In the Gothenburg COVID-19 assessment Lab, they perform COVID-19 PCR testing of samples from colleagues working at all AstraZeneca sites in Sweden. To deliver the required capacity for PCR assessments, the  Lab is currently operating in two shifts, spanning from 7 am to 9 pm, Mondays to Saturdays. They are operating under a high quality standard and they are in the process of certifying the lab to ISO 17025 standards. Therefore, we are looking for a candidate as COVID-19 Laboratory Project Coordinator as until year end.


Randstad Life Sciences is specialized in competences within Life Science. As a consultant with us, you get a competitive salary, benefits and collective agreements. Your consultant manager is always there for you and ensures that you get varying and developing assignments at different companies, within different industries. At Randstad Life Sciences, your personal development is in focus, and you are offered a large network and many social activities.

Responsibilities
The Laboratory Project Coordinator will be collaborating with the Lab team to ensure the work processes are kept according to standards set in the ISO 17025 accreditation and will report to the Sweden COVID-19 Assessment Laboratory Head. The Laboratory Project Coordinator’s primary responsibilities include:
Onboarding new personal
Ensuring all staff are documented and compliant regarding mandatory training
Daily, weekly reporting as required by ISO 17025
Responsible for weekly lab team meetings, agenda and notes
Reporting deviations from standards in quality systems
Supporting Lab Head regarding quality and SHE issue reporting
Weekly reporting to internal stakeholders as well as Swedish Health Authority (Folkhälsomyndigheten)
As member of the PCR Sweden team, ensure issues and changes to routines are communicated both to and from the lab team
Point of contact for the Assessment Centers for ad hoc questions eg. regarding sampling kits, transport of samples between lab and assessment center, daily lab capacity etc.
Holding regular meetings with Health Care Providers (HCP) providing opportunity for feedback on the process


Qualifications


Excellent communication skills and enjoys working with people in an dynamic environment
Enjoys planning, reporting and as strong attention to detail
Strong multitasking skills
Enjoys working across functions and geographies
Desirable: Previous experience in working in a regulated laboratory environment

For us, it is important that all competence and skills in the labor market are utilized. We welcome all applicants and strive for diversity.

Application
2021-07-08, selection and interviews will be ongoing. The position may be filled before the last day of application, therefore, apply as soon as possible.


For more information please contact Galia Nyström, [email protected] or Birgitta Nyström [email protected]. 

About the company
Randstad Life Sciences specializes in the field of science and is part of Randstad, the world leader in recruitment and consulting with operations in 38 countries. With this global network, in combination with our strong local foundation, we can offer a wide range of varied and developing assignments and jobs for you who are a specialist in life science. Our mission is to help you reach your true potential with your career in focus! Visa mindre

Stem & Primary Cell Team

Hays Specialist Recruitment is now looking to recruit 3 Senior Research Scientists to join the Stem & Primary Cell Team for 1 year contract assignments at AstraZeneca in Gothenburg.

We have an exciting opportunity for 3 scientists to join Discovery Sciences' Stem and Primary Cell Group. The roles will be focused on target innovation and hypothesis validation using NGS, cell based assays and PGE editing to support target identification and validation for projects across several therapy areas at AstraZeneca.

The roles
You will be based in Gothenburg Sweden, working alongside our stem cell scientists, disease areas specialists and together with our NGS and PGE team. Using your strong knowledge and experience in cell-based assay development and/or NGS and CRISPR technology you will have the opportunity to work with cutting edge cellular models of disease. This includes culture and differentiation of induced pluripotent stem cells (iPSCs) as a platform for developing disease relevant cellular models to validate target hypothesis.

The role is focused on laboratory-based activities. Your biggest impact will be through significant contributions to the practical delivery to projects in compliance with AstraZeneca corporate responsibility, policies and relevant safety standards.

It is essential to have good social and communication skills, be collaborative and a strong team player. Candidates should be able to work independently, take own initiatives and have a positive, goal oriented and problem-solving attitude.
Good organizational, data management and documentation skills are required, and you should be comfortable in presenting your results. English language is required, both spoken and in writing.

Expertise in one or more of the following areas is essential:

* Experience in cellular assay development, independently designing, developing and validating assays for implementation in drug discovery
* Experience in iPSC culture and quality control
* Application of differentiation protocols for generation of complex stem-cell based cell models
* Hands on expertise in data generation from Next Generation Sequencing technologies (e.g. RNA-seq, DNA-seq, single cell transcriptomics, nucleic acid extractions and sequencing library preparation)
* Expertise in cell biology, molecular biology and genome editing

The following skills are highly desirable:

* Expertise with liquid handling automation technologies
* Experience of high throughput transcriptomics methods
* Experience of setting up cell based pharmacological assays

Minimum experience
You should hold a B.Sc., M.Sc. or Ph.D. with corresponding experience in a relevant scientific discipline with experience in cell assay development.
For the Senior Research Scientist role, you should either hold a Ph.D. in Cellular Biology or a related degree or have significant relevant experience working with cell assay development. Visa mindre